Is Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate safe in cosmetics?
Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate
Also known as: UNII-R6MU0U9L45, 1,4-Cyclohexanedicarboxylic acid, 1,4-bis(2-(2-ethoxyethoxy)ethyl) ester, Neosolue-aqulio
INCI: BIS-ETHOXYDIGLYCOL CYCLOHEXANE 1,4-DICARBOXYLATE
Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate (CAS 922165-31-9) is a cosmetic cosmetic ingredient functioning as Emollient, Humectant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 922165-31-9 →
Auto-generated CPSR Part A draft with source citations
Function
Emollient, Humectant
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
bis[2-(2-ethoxyethoxy)ethyl] cyclohexane-1,4-dicarboxylate
InChIKey
JNFDQAYPZCYWLD-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Registered in FDA GSRS (UNII R6MU0U9L45); no specific restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate.
Regulatory Flags
emollient
humectant
penetration-enhancer
synthetic-ester
reach-registered
data-gap
Known Synonyms
UNII-R6MU0U9L45
1,4-Cyclohexanedicarboxylic acid, 1,4-bis(2-(2-ethoxyethoxy)ethyl) ester
Neosolue-aqulio
Chemical Function
Humectant
Softener and conditioner
Emulsifier
Frequently Asked Questions
Is Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate allowed in the EU?
Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate do in cosmetics?
Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate functions as: Emollient, Humectant. It is classified as a cosmetic ingredient in our database. CAS number: 922165-31-9.
Is Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate used outside cosmetics?
Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters
Excellent
Same category
Skin conditioning emollient, texturizer
Acetic/Linoleic/Palmitic Triglyceride
Excellent
Same category
Skin conditioning (emollient)
Acetyl Ornithine
Excellent
Same category
Emollient
Acetyl Proline
Excellent
Same category
Emollient
Acetyl Triethylhexyl Citrate
Excellent
Same category
Emollient, Film Forming, Plasticiser
Acetyl Trihexyl Citrate
Excellent
Same category
Plasticiser, Skin Conditioning (Emoll...
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
(ARCTIUM LAPPA/CARROT/COLOCASIA ESCULENTA/DIOSCOREA BATATAS/GARLIC/GINGER/IPOMOEA BATATAS/NELUMBO NUCIFERA/ONION/POTATO BULBS)/(CHESTNUT/CITRUS UNSHIU/EGGPLANT/FIG/GRAPE/KIWI/LYCOPERSICON ESCULENTUM/MALUS PUMILA/MUME/PEACH/PLUM/PUMPKIN/PYRUS SEROTINA/RADISH/ZIZIPHUS JUJUBA FRUIT)/(ALLIUM TUBEROSUM/ALOE BARBADENSIS/ANGELICA UTILIS/BRASSICA OLERACEA ACEPHALA/CABBAGE/CELERY/SACCHARINA JAPONICA/UNDARIA PINNATIFIDA LEAF)/(ALLIUM FISTULOSUM/ENTEROMORPHA COMPRESSA/OENANTHE JAVANICA STALK)/LENTINULA EDODES/SUCROSE FERMENT FILTRATE
Good
Similar safety
Humectant, Skin Conditioning - Humect...
BIS(1-METHYLHEPTYL) MALEATE
Good
Browse nearby
Hair Conditioning, Plasticiser, Skin ...
BIS(AMINOMETHYL)NORBORNANE
Good
Browse nearby
Not Reported
BIS(GLYCIDOXYPHENYL)PROPANE/BISAMINOMETHYLNORBORNANE COPOLYMER
Good
Browse nearby
Film Forming
Is Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate in your formulation.