NOAEL Data REACH Registered Cosmetic Ingredient

Bis-ethoxydiglycol cyclohexane 1,4-dicarboxylate

Also known as: UNII-R6MU0U9L45, 1,4-Cyclohexanedicarboxylic acid, 1,4-bis(2-(2-ethoxyethoxy)ethyl) ester, Neosolue-aqulio

CAS 922165-31-9

Bis-ethoxydiglycol cyclohexane 1,4-dicarboxylate (CAS 922165-31-9) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate →

SOURCE NOAEL studies
NOAEL studies
4
SOURCE Chemical inventory jurisdictions
Regulatory lists
0
SOURCE EU CLP Annex VI
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 9 fields
Name
Bis-ethoxydiglycol cyclohexane 1,4-dicarboxylate
CAS Number
922165-31-9
DTXSID
DTXSID20238929
Molecular Formula
C20H36O8
InChI Key
JNFDQAYPZCYWLD-UHFFFAOYSA-N
Monoisotopic Mass
404.241018
Synonyms
UNII-R6MU0U9L451,4-Cyclohexanedicarboxylic acid, 1,4-bis(2-(2-ethoxyethoxy)ethyl) esterNeosolue-aqulio

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records
HumectantSoftener and conditionerEmulsifier

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
R6MU0U9L45UNIIFDA UNII substance identifier--openFDA substances
R6MU0U9L45UNIIFDA UNII substance identifier--openFDA substances
R6MU0U9L45UNIIFDA UNII substance identifier--openFDA substances
R6MU0U9L45UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA 1 records
StatusNameEC NumberLink
RegisteredBis[2-(2-ethoxyethoxy)ethyl] cyclohexane-1,4-dicarboxylate618-829-7ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Bis-ethoxydiglycol cyclohexane 1,4-dicarboxylate?

Bis-ethoxydiglycol cyclohexane 1,4-dicarboxylate has 4 NOAEL studies in the database. The lowest reported value is R6MU0U9L45 UNII. Source: openFDA substances.

Is Bis-ethoxydiglycol cyclohexane 1,4-dicarboxylate used in cosmetics?

Yes, Bis-ethoxydiglycol cyclohexane 1,4-dicarboxylate is also indexed as a cosmetic ingredient under the name Bis-Ethoxydiglycol Cyclohexane 1,4-Dicarboxylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Bis-ethoxydiglycol cyclohexane 1,4-dicarboxylate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Bis-ethoxydiglycol cyclohexane 1,4-dicarboxylate used outside industrial chemicals?

Bis-ethoxydiglycol cyclohexane 1,4-dicarboxylate also appears in cosmetics databases.