Is Bifida Ferment Lysate safe in cosmetics?
Bifida Ferment Lysate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Active Ingredient
Bifida Ferment Lysate
INCI: BIFIDA FERMENT LYSATE
Bifida Ferment Lysate is a cosmetic active ingredient functioning as Antioxidant, Barrier Strengthening, Anti-inflammatory, Immunomodulating,. EU Regulation 1223/2009 status: permitted.
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, Barrier Strengthening, Anti-inflammatory, Immunomodulating, UV-Resilience Supporting, Anti-dandruff, Skin Conditioning, Ceramide Synthesis Stimulation, Antimicrobial Peptide Induction
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted as cosmetic ingredient; no specific FDA restrictions. UVB protection SPF 4-5 (below US SPF 2+ labeling minimum — cannot make sunscreen claims). Disease claims (eczema, dandruff treatment) = drug. MoCRA 2026 compliance required.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Bifida Ferment Lysate.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
10 property records from structured ingredient metadata.
acne
{"anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-10", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_acne": "No restriction", "…
anti_aging
{"anti_aging_claim": "barrier-repair, anti-wrinkle", "mechanism_of_action": "Bioactive phytochemicals, antioxidant compounds", "target_skin_layer": "epidermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "10-18", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "Phytothera…
anti_pollution
{"cas_number": "96507-89-0", "ingredient_class": "other", "primary_mechanism": "barrier_reinforcement/microbiome", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF…
baby_pediatric
{"cas_number": "CAS-FUNC-43", "ingredient_class": "other", "pediatric_safety_rating": "good", "minimum_age_months": "3", "neonatal_safe": "no", "premature_infant_safe": "insufficient_data", "skin_barrier_maturity_consideration": "Probiotic/postbiotic - emerging baby care", "transepidermal_absorption_risk_pediatric": "low", "systemic_exposure_concern_pediatric": "low", "dose_per_kg_body_weight_conc…
cost_pricing
{"cost_tier": "premium", "estimated_cost_per_kg_usd_low": "150", "estimated_cost_per_kg_usd_high": "280", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "medium", "primary_source_region": "Korea/Japan", "bulk_discount_threshold_kg": "5", "seasonal_price_variation": "low", "commodity_or_specialty": "specialty", "substitute_ingredients": "Saccharo…
deodorant
{"cas_number": "96507-89-0", "ingredient_class": "postbiotic_deodorant", "mechanism_of_action": "microbiome_modulation", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "12-24", "odor_reduction_pct": "45-65", "bacteriostatic": "no", "bactericidal": "no", "target_bacteria": "promotes beneficial", "microbiome_impact": "prebiotic", "axillary_microbiome_effect": "varies…
depigmentation
{"cas_number": "formulation", "ingredient_class": "keratinocyte_turnover_enhancer", "primary_mechanism_of_action": "Fermentation metabolites provide gentle brightening and barrier support", "secondary_mechanisms": "Variable", "molecular_target": "other", "tyrosinase_inhibition_IC50_uM": "varies", "tyrosinase_inhibition_type": "competitive", "melanin_reduction_pct_in_vitro": "25-45", "melanin_reduc…
ecotoxicity
{"biodegradable": "yes", "biodegradation_days": "14-28", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "very low toxicity", "freshwater_toxicity": "minimal impact", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental": "no", "palm_…
Expert Verdict
Expert safety assessment and concern-level summary for Bifida Ferment Lysate.
Regulatory Flags
postbiotic
no-live-organisms
flg-lor-ivl-tgm1-aqp3-upregulation
camp-hbd2-amp-induction
antioxidant-dpph-abts
tewl-reduction-18-22pct
ceramide-synthesis-stimulation
uvb-spf4-5-in-vitro
anti-dandruff
malassezia-immune-modulation
41pct-cytokine-reduction-combo
sensitive-skin-first-choice
supplier-amp-thiopeptide-clearance-required
batch-bioactive-profiling-critical
Frequently Asked Questions
Is Bifida Ferment Lysate allowed in the EU?
Bifida Ferment Lysate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Bifida Ferment Lysate do in cosmetics?
Bifida Ferment Lysate functions as: Antioxidant, Barrier Strengthening, Anti-inflammatory, Immunomodulating, UV-Resilience Supporting, Anti-dandruff, Skin Conditioning, Ceramide Synthesis Stimulation, Antimicrobial Peptide Induction. It is classified as a Active Ingredient in our database.
Compliance Tools
Check Bifida Ferment Lysate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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BIFIDA FERMENT EXTRACT
Good
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