Is Ashwagandha (Withania Somnifera) Root Ext safe in cosmetics?
Ashwagandha (Withania Somnifera) Root Ext has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Active Ingredient
Ashwagandha (Withania Somnifera) Root Ext
INCI: WITHANIA SOMNIFERA ROOT EXTRACT
Ashwagandha (Withania Somnifera) Root Ext (CAS 90147-43-6) is a cosmetic active ingredient functioning as Extract from roots of Withania somnifera (ashwagandha). Active constituents:. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 90147-43-6 →
Auto-generated CPSR Part A draft with source citations
Function
Extract from roots of Withania somnifera (ashwagandha). Active constituents: withanolides (steroidal lactones with anti-inflammatory, antioxidant, and adaptogenic properties), alkaloids, and saponins. Mechanisms in topical context: withanolide antioxidant and anti-inflammatory activity via NF-κB pathway inhibition; potential cortisol-modulation in stressed keratinocytes (adaptogenic claim). Strong oral evidence base for anti-stress and cortisol reduction; topical skincare evidence remains limited to in-vitro and supplier studies.
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted without restriction. Growing in clean/holistic beauty alongside other adaptogens. Topical claims must be substantiated — in-vitro withanolide activity data typically forms the evidence base. MoCRA safety substantiation required.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ashwagandha (Withania Somnifera) Root Ext.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Ashwagandha (Withania Somnifera) Root Ext.
Regulatory Flags
adaptogen
antioxidant
anti-inflammatory
holistic-beauty
claims-substantiation-required
oral-evidence-stronger-than-topical
Frequently Asked Questions
Is Ashwagandha (Withania Somnifera) Root Ext allowed in the EU?
Ashwagandha (Withania Somnifera) Root Ext EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ashwagandha (Withania Somnifera) Root Ext do in cosmetics?
Ashwagandha (Withania Somnifera) Root Ext functions as: Extract from roots of Withania somnifera (ashwagandha). Active constituents: withanolides (steroidal lactones with anti-inflammatory, antioxidant, and adaptogenic properties), alkaloids, and saponins. Mechanisms in topical context: withanolide antioxidant and anti-inflammatory activity via NF-κB pathway inhibition; potential cortisol-modulation in stressed keratinocytes (adaptogenic claim). Strong oral evidence base for anti-stress and cortisol reduction; topical skincare evidence remains limited to in-vitro and supplier studies.. It is classified as a Active Ingredient in our database. CAS number: 90147-43-6.
Compliance Tools
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MoS Calculator
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