Ashwagandha (Withania Somnifera) Root Ext

INCI: WITHANIA SOMNIFERA ROOT EXTRACT

Ashwagandha (Withania Somnifera) Root Ext (CAS 90147-43-6) is a cosmetic active ingredient functioning as Extract from roots of Withania somnifera (ashwagandha). Active constituents:. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in food safety data.

View industrial chemical safety profile for CAS 90147-43-6 →

Auto-generated CPSR Part A draft with source citations
Function
Extract from roots of Withania somnifera (ashwagandha). Active constituents: withanolides (steroidal lactones with anti-inflammatory, antioxidant, and adaptogenic properties), alkaloids, and saponins. Mechanisms in topical context: withanolide antioxidant and anti-inflammatory activity via NF-κB pathway inhibition; potential cortisol-modulation in stressed keratinocytes (adaptogenic claim). Strong oral evidence base for anti-stress and cortisol reduction; topical skincare evidence remains limited to in-vitro and supplier studies.
Safety Rating
GOOD

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted without restriction. Growing in clean/holistic beauty alongside other adaptogens. Topical claims must be substantiated — in-vitro withanolide activity data typically forms the evidence base. MoCRA safety substantiation required.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Ashwagandha (Withania Somnifera) Root Ext.

Calculate MoS for your specific formulation with the MoS Calculator.

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Antioxidant Biocide Bleaching agent Humectant Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for Ashwagandha (Withania Somnifera) Root Ext.

Regulatory Flags

adaptogen antioxidant anti-inflammatory holistic-beauty claims-substantiation-required oral-evidence-stronger-than-topical

Chemical Function

Softener and conditioner

Cross-Vertical Safety Context

Same-CAS public records found in food safety data.

SOURCE EFSA / FDA GRAS food_additives

Food Safety Data

Same-CAS food additive or FDA GRAS records from the core public database.

Food Name
Ashwagandha extract
Food Category
preservative
View full food safety profile →

Frequently Asked Questions

Is Ashwagandha (Withania Somnifera) Root Ext safe in cosmetics?

Ashwagandha (Withania Somnifera) Root Ext has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Ashwagandha (Withania Somnifera) Root Ext allowed in the EU?

Ashwagandha (Withania Somnifera) Root Ext EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ashwagandha (Withania Somnifera) Root Ext do in cosmetics?

Ashwagandha (Withania Somnifera) Root Ext functions as: Extract from roots of Withania somnifera (ashwagandha). Active constituents: withanolides (steroidal lactones with anti-inflammatory, antioxidant, and adaptogenic properties), alkaloids, and saponins. Mechanisms in topical context: withanolide antioxidant and anti-inflammatory activity via NF-κB pathway inhibition; potential cortisol-modulation in stressed keratinocytes (adaptogenic claim). Strong oral evidence base for anti-stress and cortisol reduction; topical skincare evidence remains limited to in-vitro and supplier studies.. It is classified as a Active Ingredient in our database. CAS number: 90147-43-6.

Is Ashwagandha (Withania Somnifera) Root Ext used outside cosmetics?

Ashwagandha (Withania Somnifera) Root Ext also appears in food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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