Good Active Ingredient Sensitization Data

Arctium Lappa Root Extract

Also known as: Extract of lappa, Great burdock extract, EC number: 281-658-8

INCI: ARCTIUM LAPPA ROOT EXTRACT

Arctium Lappa Root Extract (CAS 84012-13-5) is a cosmetic active ingredient functioning as Skin conditioning, antioxidant, anti-inflammatory, hair conditioning,. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 84012-13-5 →

Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, antioxidant, anti-inflammatory, hair conditioning, anti-dandruff
Safety Rating
GOOD

Chemistry & Identifiers

EC Number
281-658-8

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes No FDA restriction; no CIR monograph for root extract (seed oil reviewed separately, 2011); MoCRA product listing applies

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Arctium Lappa Root Extract.

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Arctium Lappa Root Extract based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
compositae-group
Reaction Type
contact-dermatitis

Source: IVDK; literature review

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

1 property record from structured ingredient metadata.

allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "botanical", "cross_reactivity_group": "compositae-group", "patch_test_frequency_pct": "0.3", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "IVDK; literature review"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Antioxidant Softener and conditioner
Regulatory List Membership (3)
EU Regulated in Personal Care EU Regulated in Personal Care EU Regulated in Personal Care

Expert Verdict

Expert safety assessment and concern-level summary for Arctium Lappa Root Extract.

Regulatory Flags

botanical data-gap no-cir-review asteraceae-cross-reactivity sensitizer-suspected

Known Synonyms

Extract of lappa Great burdock extract EC number: 281-658-8

Chemical Function

Antioxidant Softener and conditioner Astringent Humectant

Regulatory Lists

Europe Personal care - hair styling and care - shampoo-dandruff Europe Personal care - hair styling and care - shampoo-dandruff Europe Personal care Europe Personal care Europe Personal care Europe Personal care Europe Personal care Europe Personal care Europe Personal care - body oil

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA count match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Adverse Event Associations
14
View full pharmaceutical profile →

Frequently Asked Questions

Is Arctium Lappa Root Extract safe in cosmetics?

Arctium Lappa Root Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Arctium Lappa Root Extract allowed in the EU?

Arctium Lappa Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Arctium Lappa Root Extract do in cosmetics?

Arctium Lappa Root Extract functions as: Skin conditioning, antioxidant, anti-inflammatory, hair conditioning, anti-dandruff. It is classified as a Active Ingredient in our database. CAS number: 84012-13-5.

Is Arctium Lappa Root Extract used outside cosmetics?

Arctium Lappa Root Extract also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
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(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
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(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
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Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good Similar safety
Antioxidant
AVENA SATIVA KERNEL EXTRACT
Good Chemical family
Botanical / Natural ingredient
Arctium Lappa Fruit Extract
Good Chemical family
Skin Conditioning
Arctium Lappa Leaf Extract
Good Chemical family
Skin Conditioning

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