Aqua

Also known as: EC No.: 231-791-2, 231-791-2, EINECS 231-791-2, Water, deionized, Water, mineral (+15 more)

INCI: AQUA

Aqua (CAS 7732-18-5) is a cosmetic cosmetic ingredient functioning as Solvent, continuous phase carrier in O/W emulsions. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 7732-18-5 →

Auto-generated CPSR Part A draft with source citations
Function
Solvent, continuous phase carrier in O/W emulsions
Safety Rating
EXCELLENT

Chemistry & Identifiers

Formula
H2O
MW
18.015 g/mol
PubChem CID
962
IUPAC Name
oxidane
InChIKey
XLYOFNOQVPJJNP-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes No FDA restriction. Labeled as WATER in US. VCRP universal acceptance.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Aqua.

Calculate MoS for your specific formulation with the MoS Calculator.

EPA ToxValDB — Toxicity Values

2 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
NOEL =1000 mg/kg-day Rat oral - ECHA IUCLID
LD50 >90 mL/kg Rat oral - ChemIDplus

Expanded Dermal Absorption Data

Cross-database dermal penetration: EPA Dryad physics-based, Roberts Mendeley permeation, and SCCS-aggregated measured values.

EPA Dryad Skin Absorption (physics-based)
MW: 18.015
LogP: -1.38
Kp epidermis: 0.99586 cm/h

Source: EPA_Dryad_Skin_Absorption_2024

Roberts Skin Permeation (Mendeley 2022)
MW: 18
Log Kow: -1.38
Log Kp: -2.8068754016455384
Log Jmax: -4.06

Source: Roberts_Cheruvu_Mendeley_2022

Typical Use Concentrations

Reported concentration ranges per product category from SCCS/CIR/industry sources.

Product Category Typical Range Max Reported Source
Face Cream 70–85 92 CIR/Industry
Body Lotion 70–85 90 CIR/Industry
Shampoo 55–75 85 CIR/Industry
Conditioner 50–70 80 CIR/Industry
Serum 80–90 96 CIR/Industry
Toner 85–95 98 CIR/Industry

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Adhesion/cohesion promoter Anti-adhesive/cohesive Binder Catalyst Chelating agent Cleaning agent Defoamer Degradant/impurity Dehydrating agent (desiccant) Diluent
Regulatory List Membership (5)
EU Regulated in Personal Care EU Restricted for Children (Cosmetics) IFRA Fragrance Transparency List EPA Safer Chemical Ingredients List (SCIL) Consumer Product Chemical

Expert Verdict

Expert safety assessment and concern-level summary for Aqua.

Regulatory Flags

microbiological-control-required eu_children_restricted epa_safer_alternative ifra_fragrance

Known Synonyms

EC No.: 231-791-2 231-791-2 EINECS 231-791-2 Water, deionized Water, mineral Water vapor Dihydrogen Monoxide Sterile water Water, sterile Bacteriostatic water for injection in plastic container Sterile water for injection in plastic container Sterile water in plastic container UNII-059QF0KO0R Bacteriostatic water for injection Sterile purified water Sterile water for inhalation Sterile water for injection Sterile water for irrigation Water for hemodialysis Water for inhalation, sterile

Chemical Function

Solvent

Regulatory Lists

children; Europe; Personal care children; Europe; Personal care - specialized bath products - bath salts children; Europe; Personal care children; Europe; Personal care - general moisturizing - hand/body lotion children; Europe; Personal care - body hygiene - body wash children; Europe; Personal care - hair styling and care - shampoo children; Europe; Personal care - specialized bath products - bubble bath children; Europe; Personal care - dental care - toothpaste children; Europe; Personal care Europe; Personal care - hair styling and care - shampoo-dandruff Europe; Personal care - liniment Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care - oral and dental care - teeth whitener

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
WATER
ChEMBL ID
CHEMBL1098659
Max Phase
4
Adverse Event Associations
1859
View full pharmaceutical profile →

Frequently Asked Questions

Is Aqua safe in cosmetics?

Aqua has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.

Is Aqua allowed in the EU?

Aqua EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aqua do in cosmetics?

Aqua functions as: Solvent, continuous phase carrier in O/W emulsions. It is classified as a cosmetic ingredient in our database. CAS number: 7732-18-5.

Is Aqua used outside cosmetics?

Aqua also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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