Is Anserine safe in cosmetics?
Anserine has a safety rating of "GOOD" in our database. EU status: permitted. US status: restricted.
Good
Cosmetic Ingredient
Anserine
Also known as: L-Histidine, β-alanyl-3-methyl-, N-(3-Amino-1-hydroxypropylidene)-3-methylhistidine, L-Histidine, N-β-alanyl-3-methyl-, Histidine, N-β-alanyl-3-methyl-, L-, β-Alanyl-3-methyl-L-histidine (+7 more)
INCI: ANSERINE
Anserine (CAS 584-85-0) is a cosmetic cosmetic ingredient functioning as Antioxidant, Humectant, Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 584-85-0 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, Humectant, Skin Conditioning
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
Not specifically restricted; dipeptide (β-alanine + 3-methyl-L-histidine) generally regarded as low-risk
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Anserine.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Anserine.
Known Synonyms
L-Histidine, β-alanyl-3-methyl-
N-(3-Amino-1-hydroxypropylidene)-3-methylhistidine
L-Histidine, N-β-alanyl-3-methyl-
Histidine, N-β-alanyl-3-methyl-, L-
β-Alanyl-3-methyl-L-histidine
L-Anserine
Marine Active
(2S)-2-(3-Aminopropanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoic acid
1: PN: WO2009033771 PAGE: 100 claimed protein
EINECS 209-545-0
EC No.: 209-545-0
209-545-0
Chemical Function
Humectant
Antioxidant
Softener and conditioner
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ANSERINE
ChEMBL ID
CHEMBL448301
Frequently Asked Questions
Is Anserine allowed in the EU?
Anserine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Anserine do in cosmetics?
Anserine functions as: Antioxidant, Humectant, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 584-85-0.
Is Anserine used outside cosmetics?
Anserine also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Anserine compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
2-O-Ethyl Ascorbic Acid
Excellent
Same category
Softener and conditioner
3-Glyceryl Ascorbate
Excellent
Same category
Antioxidant, Humectant, Skin Conditio...
Allantoin Ascorbate
Excellent
Same category
Antioxidant, Skin Conditioning, Skin ...
Aloe Vera Extract
Excellent
Same category
Skin Conditioning, Antioxidant
Althaea Officinalis Callus Culture Extract
Excellent
Same category
Antioxidant, skin protectant
Amaranthus Caudatus Seed Oil
Excellent
Same category
Emollient, skin conditioning, antioxi...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ARCTIUM LAPPA/CARROT/COLOCASIA ESCULENTA/DIOSCOREA BATATAS/GARLIC/GINGER/IPOMOEA BATATAS/NELUMBO NUCIFERA/ONION/POTATO BULBS)/(CHESTNUT/CITRUS UNSHIU/EGGPLANT/FIG/GRAPE/KIWI/LYCOPERSICON ESCULENTUM/MALUS PUMILA/MUME/PEACH/PLUM/PUMPKIN/PYRUS SEROTINA/RADISH/ZIZIPHUS JUJUBA FRUIT)/(ALLIUM TUBEROSUM/ALOE BARBADENSIS/ANGELICA UTILIS/BRASSICA OLERACEA ACEPHALA/CABBAGE/CELERY/SACCHARINA JAPONICA/UNDARIA PINNATIFIDA LEAF)/(ALLIUM FISTULOSUM/ENTEROMORPHA COMPRESSA/OENANTHE JAVANICA STALK)/LENTINULA EDODES/SUCROSE FERMENT FILTRATE
Good
Similar safety
Humectant, Skin Conditioning - Humect...
(ASPERGILLUS/SACCHAROMYCES)/RICE FERMENT/BARLEY GRAIN MEAL/NELUMBO NUCIFERA FLOWER EXTRACT FERMENT EXTRACT FILTRATE
Good
Similar safety
Bleaching
(ASTRAGALUS MEMBRANACEUS/GLYCYRRHIZA URALENSIS (LICORICE)/PANAX GINSENG) ROOT/AMOMUM XANTHIOIDES SEED/HORDEUM VULGARE SPROUT/ARALIA CORDATA/ACHYRANTHES JAPONICA EXTRACT
Good
Similar safety
Skin Conditioning - Miscellaneous
1,2-Butanediol
Good
Chemical family
Solvent, humectant, skin conditioning
ALLETHRINS
Good
Chemical family
Fragrance, Skin Conditioning
Potassium Carbonate
Good
Chemical family
Buffering agent, pH adjuster
Is Anserine in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Anserine in your formulation.