What is the NOAEL for N-(3-Amino-1-hydroxypropylidene)-3-methylhistidine?
N-(3-Amino-1-hydroxypropylidene)-3-methylhistidine has 4 NOAEL studies in the database. The lowest reported value is HDQ4N37UGV UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
N-(3-Amino-1-hydroxypropylidene)-3-methylhistidine
Also known as: L-Histidine, β-alanyl-3-methyl-, L-Histidine, N-β-alanyl-3-methyl-, Histidine, N-β-alanyl-3-methyl-, L-, β-Alanyl-3-methyl-L-histidine, L-Anserine (+6 more)
CAS 584-85-0
N-(3-Amino-1-hydroxypropylidene)-3-methylhistidine (CAS 584-85-0) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
N-(3-Amino-1-hydroxypropylidene)-3-methylhistidine
CAS Number
584-85-0
DTXSID
DTXSID30973950
Molecular Formula
C10H16N4O3
InChI Key
MYYIAHXIVFADCU-QMMMGPOBSA-N
Monoisotopic Mass
240.12224
Synonyms
L-Histidine, β-alanyl-3-methyl-L-Histidine, N-β-alanyl-3-methyl-Histidine, N-β-alanyl-3-methyl-, L-β-Alanyl-3-methyl-L-histidineL-AnserineMarine Active(2S)-2-(3-Aminopropanamido)-3-(1-methyl-1H-imidazol-5-yl)propanoic acid1: PN: WO2009033771 PAGE: 100 claimed proteinEINECS 209-545-0EC No.: 209-545-0209-545-0
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
HumectantAntioxidantSoftener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| HDQ4N37UGV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HDQ4N37UGV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HDQ4N37UGV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| HDQ4N37UGV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ANSERINE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
Is N-(3-Amino-1-hydroxypropylidene)-3-methylhistidine used in cosmetics?
Yes, N-(3-Amino-1-hydroxypropylidene)-3-methylhistidine is also indexed as a cosmetic ingredient under the name Anserine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for N-(3-Amino-1-hydroxypropylidene)-3-methylhistidine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is N-(3-Amino-1-hydroxypropylidene)-3-methylhistidine used outside industrial chemicals?
N-(3-Amino-1-hydroxypropylidene)-3-methylhistidine also appears in cosmetics, pharmaceutical, food safety databases.