NOAEL Studies
Fragrance
Amyl Cinnamal NOAEL Studies
INCI: AMYL CINNAMAL
CAS: 122-40-7
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
COSMOS_DB 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| COSMOS_DB | NOAEL | 300 | mg/kg bw/day | rat | oral | 98 day | Subchronic | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
| COSMOS_DB | NOAEL | 6 | mg/kg bw/day | rat | oral | 90 day | Subchronic | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx | NOAEL | =30 | mg/kg bw/day | Rat | oral: feed | 98 days | subchronic | EFSA FEEDAP - 2017 - OutputID 2920 - organ weights - systemic - Safety and efficacy of aryl-substituted primary alcohol, aldehyde, acid, ester and acetal derivatives belonging to chemical group 22 when used as flavourings for all animal species - doi:10.2903/j.efsa.2017.4672 |
| EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx | NOAEL | =30 | mg/kg bw/day | Rat | oral: feed | 98 days | subchronic | EFSA FEEDAP - 2017 - OutputID 2920 - organ weights - systemic - Safety and efficacy of aryl-substituted primary alcohol, aldehyde, acid, ester and acetal derivatives belonging to chemical group 22 when used as flavourings for all animal species - doi:10.2903/j.efsa.2017.4672 |
INCHEM_WHO_harmproj_harmproj_harmproj10 25 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| INCHEM_WHO_harmproj_harmproj_harmproj10 | ADI | range:0-0.020.02 | mg/kg bw/day | - | - | - | Health guidance value | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=29e3151730555ba9; raw_unit=mg/kg body weight; context=This finding is of particular interest, because significant enhancement was at a dose that is lower than the upper end of the WHO-established ADI of 0-0.02 mg/kg body weight (FAO/WHO, 1998). |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | ADI | range:0-0.50.5 | mg/kg bw/day | - | oral | - | Health guidance value | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=2327525ce65744e0; raw_unit=mg/kg body weight; context=The Joint FAO/WHO Expert Committee on Food Additives has evaluated citral as a food additive and has derived a group ADI of 0-0.5 mg/kg body weight (expressed as citral) for a group of terpenoid flavouring agents, including citral, citronellol, geranyl acetate, linalool and linalyl acetate (FAO/WHO, 2004). |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =1036 | mg/L | - | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=cdf6dfe1abd73db0; raw_unit=mg/l; context=The LOAEL for lead acetate in this study was 1036 mg/l, with a corres- ponding BLL of 20.5 ± 1.1 ug/dl. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =512 | mg/L | - | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=db7452ca9955e155; raw_unit=mg/l; context=Therefore, the 512 mg/l dose with the corresponding BLL of 87 ug/dl was used as a LOAEL. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =0.2 | mg/kg bw/day | Rat | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=80b3d8dddb245c80; raw_unit=mg/kg body weight per day; context=Therefore, a LOAEL of 0.2 mg/kg body weight per day in rats following perinatal exposure was chosen as the POD for the derivation of an AEL. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =0.0004 | mg/m3 | Human | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=8da1e9656bd16e1d; raw_unit=ng/m3; unit_normalization=converted from nanograms; context=Baker et al. (1990) and Brooks et al. (1990) report sensitization in 11% of workers down to the lowest soluble platinum level (LOAEL = 400 ng/m3); however, they reported a higher concentration (600 ng/m3 soluble platinum) in an area associated with no positive SPTs (0/15 in the offices) than in other work areas associated with positive SPT (e.g. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =0.002 | mg/m3 | - | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=37b933c3b86b0fc0; raw_unit=ug/m3; unit_normalization=converted from micrograms; context=Absolute platinum concentrations were not reported in Linnett & Hughes (1999), and a clear LOAEL is not identified, because the data are reported as relative frequency of exposure levels above and below 2 ug/m3 of soluble platinum. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =0.00005 | mg/m3 | - | inhalation | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=e133a01bfc1359b0; raw_unit=ng/m3; unit_normalization=converted from nanograms; context=The WHO (2000) report on platinum in air quality guidelines for Europe reported a LOAEL based on these studies of 50 ng/m3 for platinum allergic sensitization. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =6 | mg/m3 | - | - | 5 days | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=1e2dc6a5299bab8a; raw_unit=mg/m3; context=C3.1, the LOAEL of 52.9 ng/m based on these data is supported by data from Bolm-Audorff Guidance for Immunotoxicity Risk Assessment for Chemicals 237 NOAELADJ = 3.37 × 10−6 mg/m3 × (10 m3/day / 20 m3/day) × 5 days / 7 days = 1.20 × 10−6 mg of soluble platinum per cubic metre To complete the derivation of a health-based guidance value (e.g. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =0.5 | mg/L | Mouse | oral | 10 weeks | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=cff12248ef89de2e; raw_unit=mg/l; context=The LOAEL from the studies was 0.5 mg/l for mercury(II) chloride in drinking-water for 10 weeks in male and female A.SW mice, and the effect was increased titre of antifibrillarin autoantibodies. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =0.08 | mg/kg bw/day | - | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=6fd7f38fab2105f3; raw_unit=mg/kg body weight per day; context=ecause kidney is a Guidance for Immunotoxicity Risk Assessment for Chemicals 279 Male LOAEL = 0.5 mg/l × (0.0033 l/day) / (0.0221 kg body weight) = 0.075 mg/kg body weight per day LOAEL = 0.08 mg/kg body weight per day in both sexes, rounded to one significant digit Female NOAEL = 0.25 mg/l × (0.0029 l/day) / (0.018 35 kg body weight) = 0.0395 mg/kg body weight per day NOAEL = 0.04 mg/kg body weight per day, rounded to one significant digit To continue the illustration of t |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =5 | mg/L | Mouse | oral | 10 weeks | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=a3327d53c7d84742; raw_unit=mg/l; context=For example, the LOAEL for increased renal deposits of IgG in female SJL mice given mercury(II) chloride in drinking-water for 10 weeks was 5 mg/l, with a NOAEL of 2.5 mg/l (Hultman & Enestrom, 1992). |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =0.00066 | mg/g | Mouse | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=b738b1c5b8a5ceee; raw_unit=ug/g; unit_normalization=converted from micrograms; context=The kidney level of mercury in the female BXSB mice at the LOAEL (0.66 ug/g wet weight) is compar- able to the concentration reported in female A.SW mice at the LOAEL (0.71 ug/g wet weight) and suggests the potential utility of this dose metric. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =0.00071 | mg/g | Mouse | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=e6fd2bd752cddcaa; raw_unit=ug/g; unit_normalization=converted from micrograms; context=The kidney level of mercury in the female BXSB mice at the LOAEL (0.66 ug/g wet weight) is compar- able to the concentration reported in female A.SW mice at the LOAEL (0.71 ug/g wet weight) and suggests the potential utility of this dose metric. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =1.4 | mg/L | Mouse | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=950826aeb9e20c6e; raw_unit=mg/l; context=The LOAEL of 1.4 mg/l for TCE data in B63CF1 mice from Keil et al. (2009) is for several autoimmune-related end-points in a non-autoimmune disease-prone mouse strain. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | LOAEL | =0.19 | mg/kg bw/day | - | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=4a88522e363c1718; raw_unit=mg/kg body weight per day; context=004 l/day) / (0.030 kg body weight) = 0.187 mg/kg body weight per day = 0.19 mg/kg body weight per day in both sexes To continue the illustration of this case-study, the converted LOAEL of 0.19 mg/kg body weight per day for TCE from the Keil et al. (2009) study will be used to derive the health- assessor should apply BMD modelling to the data to derive a POD near the low end of the available data. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | NOAEL | <0.00005 | mg/m3 | Human | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=2c12d1967747b971; raw_unit=ng/m3; unit_normalization=converted from nanograms; context=(1990) <500 51 88% of personal samples were <50 ng/m3 6% of samples were 500-1000 ng/m3 Linnett & Hughes (1999) NOAEL 3.37 - Stationary samples Merget et al. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | NOAEL | =0.0000529 | mg/m3 | - | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=68f6558d2ad34d1b; raw_unit=ng/m3; unit_normalization=converted from nanograms; context=(2000) of 52.9 ng/m3 could also be used as a POD to illustrate the support for the NOAEL in this study, given the range of platinum expo- 3 et al. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | NOAEL | =0.00000337 | mg/m3 | - | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=c5d2bb43dc4606ff; raw_unit=ng/m3; unit_normalization=converted from nanograms; context=Reference values based on the LOAELs would differ by less than a factor of 3 (1.48-2.37) from the reference value based on the NOAEL of 3.37 ng/m3 from Merget et al. (2000). |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | NOAEL | =0.5 | mg/L | Mouse | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=01e1de9b9eebd55c; raw_unit=mg/l; context=The 0.25 mg/l dose of mercury(II) chloride represented a NOAEL in female A.SW mice, and a no-effect level was not deter- mined in males, because the lowest dose tested in males was 0.5 mg/l (Hultman & Nielsen, 2001). |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | NOAEL | =0.25 | mg/L | Mouse | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=59c13bbf3ec4230b; raw_unit=mg/l; context=NR, not relevant a 0.25 mg/l was the NOAEL for autoantibodies to nuclear protein fibrillarin in females. b 0.5 mg/l was the LOAEL for autoantibodies to nuclear protein fibrillarin in males and females. c The authors reported that one male mouse had an extremely high AFA titre (10 240) that was not obs |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | NOAEL | =0.04 | mg/kg bw/day | - | - | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=97564aa779388c35; raw_unit=mg/kg body weight per day; context=mg/kg body weight per day in both sexes, rounded to one significant digit Female NOAEL = 0.25 mg/l × (0.0029 l/day) / (0.018 35 kg body weight) = 0.0395 mg/kg body weight per day NOAEL = 0.04 mg/kg body weight per day, rounded to one significant digit To continue the illustration of this case-study, the adjusted NOAEL of 0.04 mg/kg body weight per day for mercury(II) chloride from the Hultman and Nielsen study (Hultman & Nielsen, 2001; |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | NOAEL | =2.5 | mg/L | Mouse | oral | 10 weeks | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=d15d100dfd2f46f9; raw_unit=mg/l; context=For example, the LOAEL for increased renal deposits of IgG in female SJL mice given mercury(II) chloride in drinking-water for 10 weeks was 5 mg/l, with a NOAEL of 2.5 mg/l (Hultman & Enestrom, 1992). |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | NOAEL | =0.0000847 | mg/g | Mouse | dermal | - | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=94feec83268db0b5; raw_unit=ug/g; unit_normalization=converted from micrograms; context=The subcutaneous exposure in Pollard et al. (2001) resulted in a mean mercury level in the kidney of 0.0762 ± 0.006 ug/g wet weight at the NOAEL of 0.04 ug of mercury(II) chloride and 0.6627 ± 0.0847 ug/g wet weight at the LOAEL of 0.4 ug of mercury(II) chloride in female BXSB mice. |
| INCHEM_WHO_harmproj_harmproj_harmproj10 | NOEL | =0.00085 | mg/m3 | - | - | 5 days | Toxicology study | document_id=harmproj_harmproj_harmproj10; title=Harmonization Project Document No. 10: Guidance for Immunotoxicity Risk Assessment for Chemicals; path=mirror/documents/harmproj/harmproj/harmproj10.pdf; row_hash=133583b2d1f13c81; raw_unit=ug/m3; unit_normalization=converted from micrograms; context=exposures were (61.7 mg/m3)·h for the 0.14 mg/m3 group, compared with a (26.7 mg/m3)·h aggregate exposure that had induced antibody formation at 1.8 ug/m3 (3 hours/day for 5 days, NOEL 0.85 ug/m3) in the Karol (1983) study. |
NTP_ICE_endocrine 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_endocrine | AC50 | 32.7598234957921 | uM | - | - | - | ERPathway2016; ER Pathway Model, Antagonist | sheet=Integrated_approaches; excel_row=4768; RecordID=ERPathway2016_410; DatasetName=ERPathway2016; DTXSID=DTXSID8029157; Assay=ER Pathway Model, Antagonist; Endpoint=AC50; Response=32.7598234957921; Response_Unit=uM; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_endocrine | ACC | 50.2937959418898 | uM | - | - | - | ERPathway2016; ER Pathway Model, Antagonist | sheet=Integrated_approaches; excel_row=4769; RecordID=ERPathway2016_410; DatasetName=ERPathway2016; DTXSID=DTXSID8029157; Assay=ER Pathway Model, Antagonist; Endpoint=ACC; Response=50.2937959418898; Response_Unit=uM; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_endocrine | Model Score | 0 | unitless | - | - | - | ARPathway2016; AR Pathway Model, Antagonist | sheet=Integrated_approaches; excel_row=4764; RecordID=ARPathway2016_698; DatasetName=ARPathway2016; DTXSID=DTXSID8029157; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_endocrine | Model Score | 0.00842 | unitless | - | - | - | ERPathway2016; ER Pathway Model, Agonist | sheet=Integrated_approaches; excel_row=4770; RecordID=ERPathway2016_410; DatasetName=ERPathway2016; DTXSID=DTXSID8029157; Assay=ER Pathway Model, Agonist; Endpoint=Model Score; Response=0.00842; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
NTP_ICE_skin_sensitization 25 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_skin_sensitization | CD54, EC200 | 25.94 | ug/mL | - | Dermal | - | In Vitro; CE_hCLAT2018; h-CLAT | sheet=Data_invitro; excel_row=2159; Record_ID=skin_sensitization_invitro_533; Data_Type=In Vitro; Internal_Data_Source=CE_hCLAT2018; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=h-CLAT; Endpoint=CD54, EC200; Reported_Response=25.94; Reported_Response_Unit=ug/mL; Response=25.94; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | CD86, EC150 | 24.9 | ug/mL | - | Dermal | - | In Vitro; Urbisch_SkinSensitization2020; U-SENS | sheet=Data_invitro; excel_row=8230; Record_ID=skin_sensitization_invitro_2253; Data_Type=In Vitro; Internal_Data_Source=Urbisch_SkinSensitization2020; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=U-SENS; Endpoint=CD86, EC150; Reported_Response=123.0875701; Reported_Response_Unit=uM; Conversion_Factor_Value=202.297; Conversion_Factor_Source=EPA Dashboard; Converted_Response=24.9; Converted_Response_Unit=ug/mL; Response=24.9; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | CD86, EC150 | 13.13 | ug/mL | - | Dermal | - | In Vitro; CE_USENSE2018; U-SENS | sheet=Data_invitro; excel_row=8578; Record_ID=skin_sensitization_invitro_2368; Data_Type=In Vitro; Internal_Data_Source=CE_USENSE2018; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=U-SENS; Endpoint=CD86, EC150; Reported_Response=13.13; Reported_Response_Unit=ug/mL; Response=13.13; Response_Unit=ug/mL; Reference=Piroird et al. 2015; 25820135; 10.1016/j.tiv.2015.03.009; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | CV70 | 27.48 | ug/mL | - | Dermal | - | In Vitro; CE_USENSE2018; U-SENS | sheet=Data_invitro; excel_row=8579; Record_ID=skin_sensitization_invitro_2368; Data_Type=In Vitro; Internal_Data_Source=CE_USENSE2018; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=U-SENS; Endpoint=CV70; Reported_Response=27.48; Reported_Response_Unit=ug/mL; Response=27.48; Response_Unit=ug/mL; Reference=Piroird et al. 2015; 25820135; 10.1016/j.tiv.2015.03.009; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | CV75 | 24.2 | ug/mL | - | Dermal | - | In Vitro; CE_hCLAT2018; h-CLAT | sheet=Data_invitro; excel_row=2157; Record_ID=skin_sensitization_invitro_533; Data_Type=In Vitro; Internal_Data_Source=CE_hCLAT2018; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=h-CLAT; Endpoint=CV75; Reported_Response=24.2; Reported_Response_Unit=ug/mL; Response=24.2; Response_Unit=ug/mL; Reference=Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | Depletion Cys | 0.6 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=1209; Record_ID=skin_sensitization_invitro_327; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=DPRA; Endpoint=Depletion Cys; Reported_Response=0.6; Reported_Response_Unit=%; Response=0.6; Response_Unit=%; Reference=Gerberick et al. 2007; 17400584; 10.1093/toxsci/kfm064|Natsch et al. 2013; 23576290; 10.1002/jat.2868|Nukada et al. 2013; 23149339; 10.1016/j.tiv.2012.11.006; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | Depletion Lys | 3.9 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=1207; Record_ID=skin_sensitization_invitro_327; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=DPRA; Endpoint=Depletion Lys; Reported_Response=3.9; Reported_Response_Unit=%; Response=3.9; Response_Unit=%; Reference=Gerberick et al. 2007; 17400584; 10.1093/toxsci/kfm064|Natsch et al. 2013; 23576290; 10.1002/jat.2868|Nukada et al. 2013; 23149339; 10.1016/j.tiv.2012.11.006; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | Depletion Lys + Cys | 2.25 | % | - | Dermal | - | In Vitro; DPRA2015; DPRA | sheet=Data_invitro; excel_row=1211; Record_ID=skin_sensitization_invitro_327; Data_Type=In Vitro; Internal_Data_Source=DPRA2015; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=DPRA; Endpoint=Depletion Lys + Cys; Reported_Response=2.25; Reported_Response_Unit=%; Response=2.25; Response_Unit=%; Reference=Gerberick et al. 2007; 17400584; 10.1093/toxsci/kfm064|Natsch et al. 2013; 23576290; 10.1002/jat.2868|Nukada et al. 2013; 23149339; 10.1016/j.tiv.2012.11.006; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | EC1.5 | 14.398 | uM | - | Dermal | - | In Vitro; CE_KeratinoSense2018; KeratinoSens | sheet=Data_invitro; excel_row=4966; Record_ID=skin_sensitization_invitro_1149; Data_Type=In Vitro; Internal_Data_Source=CE_KeratinoSense2018; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=KeratinoSens; Endpoint=EC1.5; Reported_Response=14.398; Reported_Response_Unit=uM; Response=14.398; Response_Unit=uM; Reference=Natsch et al. 2013; 23576290; 10.1002/jat.2868|Joint Research Centre of the European Union 2014|Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | EC1.5 | >2000 | uM | - | Dermal | - | In Vitro; KeratinoSens2015; KeratinoSens | sheet=Data_invitro; excel_row=4968; Record_ID=skin_sensitization_invitro_1150; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=KeratinoSens; Endpoint=EC1.5; Response_Modifier=>; Reported_Response_Modifier=>; Reported_Response=2000; Reported_Response_Unit=uM; Response=2000; Response_Unit=uM; Reference=Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | EC3 | >2000 | uM | - | Dermal | - | In Vitro; CE_KeratinoSense2018; KeratinoSens | sheet=Data_invitro; excel_row=5020; Record_ID=skin_sensitization_invitro_1149; Data_Type=In Vitro; Internal_Data_Source=CE_KeratinoSense2018; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=KeratinoSens; Endpoint=EC3; Response_Modifier=>; Reported_Response_Modifier=>; Reported_Response=2000; Reported_Response_Unit=uM; Response=2000; Response_Unit=uM; Reference=Natsch et al. 2013; 23576290; 10.1002/jat.2868|Joint Research Centre of the European Union 2014|Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | EC3 | 10.6 | % | Mouse | Dermal | - | In Vivo; LLNAdb2013; LLNA | sheet=Data_invivo; excel_row=13210; Record_ID=skin_sensitization_invivo_3274; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=LLNA; Endpoint=EC3; Response=10.6; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Gerberick et al. 2005; 16536334; Not available; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | EC3 | 10.6 | % | Mouse | Dermal | - | In Vivo; LLNAdb2013; LLNA | sheet=Data_invivo; excel_row=13210; Record_ID=skin_sensitization_invivo_3274; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=LLNA; Endpoint=EC3; Response=10.6; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Gerberick et al. 2005; 16536334; Not available; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | EC3 | 10.6 | % | Mouse | Dermal | - | In Vivo; LLNAdb2013; LLNA | sheet=Data_invivo; excel_row=13210; Record_ID=skin_sensitization_invivo_3274; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=LLNA; Endpoint=EC3; Response=10.6; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Gerberick et al. 2005; 16536334; Not available; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | EC3 | 10.6 | % | Mouse | Dermal | - | In Vivo; LLNAdb2013; LLNA | sheet=Data_invivo; excel_row=13210; Record_ID=skin_sensitization_invivo_3274; Data_Type=In Vivo; Internal_Data_Source=LLNAdb2013; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=LLNA; Endpoint=EC3; Response=10.6; Response_Unit=%; Species=Mouse; Route=Dermal; Reference=Gerberick et al. 2005; 16536334; Not available; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | IC50 | 46.77 | uM | - | Dermal | - | In Vitro; CE_KeratinoSense2018; KeratinoSens | sheet=Data_invitro; excel_row=5021; Record_ID=skin_sensitization_invitro_1149; Data_Type=In Vitro; Internal_Data_Source=CE_KeratinoSense2018; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=46.77; Reported_Response_Unit=uM; Response=46.77; Response_Unit=uM; Reference=Natsch et al. 2013; 23576290; 10.1002/jat.2868|Joint Research Centre of the European Union 2014|Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | IC50 | 51 | uM | - | Dermal | - | In Vitro; KeratinoSens2015; KeratinoSens | sheet=Data_invitro; excel_row=5022; Record_ID=skin_sensitization_invitro_1150; Data_Type=In Vitro; Internal_Data_Source=KeratinoSens2015; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=KeratinoSens; Endpoint=IC50; Reported_Response=51; Reported_Response_Unit=uM; Response=51; Response_Unit=uM; Reference=Natsch et al. 2013; 23576290; 10.1002/jat.2868; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | Imax | 1.57 | ratio | - | Dermal | - | In Vitro; CE_KeratinoSense2018; KeratinoSens | sheet=Data_invitro; excel_row=5023; Record_ID=skin_sensitization_invitro_1149; Data_Type=In Vitro; Internal_Data_Source=CE_KeratinoSense2018; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=KeratinoSens; Endpoint=Imax; Reported_Response=1.57; Reported_Response_Unit=Unitless; Response=1.57; Response_Unit=Ratio; Reference=Natsch et al. 2013; 23576290; 10.1002/jat.2868|Joint Research Centre of the European Union 2014|Urbisch et al. 2015; 25541156; 10.1016/j.yrtph.2014.12.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | Incidence of positive responses | 0 | % | Human | Dermal | - | In Vivo; HPPT2020WIP; Human Maximization Test | sheet=Data_invivo; excel_row=4309; Record_ID=skin_sensitization_invivo_1042; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=6.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=Human Maximization Test; Endpoint=Incidence of positive responses; Response=0; Response_Unit=%; Species=Human; Route=Dermal; Reference=Greif 1967; Not available; Not available|Api et al. 2015; 25636726; 10.1016/j.fct.2015.01.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | Induction dose per skin area | 3724 | ug/cm2 | Human | Dermal | - | In Vivo; HPPT2020WIP; Human Maximization Test | sheet=Data_invivo; excel_row=4307; Record_ID=skin_sensitization_invivo_1042; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=6.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=Human Maximization Test; Endpoint=Induction dose per skin area; Response=3724; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=Greif 1967; Not available; Not available|Api et al. 2015; 25636726; 10.1016/j.fct.2015.01.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | Induction dose per skin area | 3888 | ug/cm2 | Human | Dermal | - | In Vivo; HPPT2020WIP; Human Maximization Test | sheet=Data_invivo; excel_row=4315; Record_ID=skin_sensitization_invivo_1043; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=6.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=Human Maximization Test; Endpoint=Induction dose per skin area; Response=3888; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=Letizia and Api 2002; Not available; Not available|Api et al. 2015; 25636726; 10.1016/j.fct.2015.01.008|Api et al. 2015; 25430073; 10.3109/15569527.2014.979425; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | Induction dose per skin area | 23620 | ug/cm2 | Human | Dermal | - | In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test | sheet=Data_invivo; excel_row=4323; Record_ID=skin_sensitization_invivo_1045; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=20.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=Human Repeat Insult Patch Test; Endpoint=Induction dose per skin area; Response=23620; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=RIFM 2001; https://www.rifm.org/rifm-science-database.php#gsc.tab=0|Letizia and Api 2002; Not available; Not available|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|Api et al. 2008; 18406028; 10.1016/j.yrtph.2007.10.008|Natsch et al. 2013; 23576290; 10.1002/jat.2868|Api et al. 2015; 25430073; 10.3109/15569527.2014.979425; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | Relative reliability score | 2 | unitless | Human | Dermal | - | In Vivo; HPPT2020WIP; Human Maximization Test | sheet=Data_invivo; excel_row=4313; Record_ID=skin_sensitization_invivo_1042; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=6.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=Human Maximization Test; Endpoint=Relative reliability score; Response=2; Response_Unit=Unitless; Species=Human; Route=Dermal; Reference=Greif 1967; Not available; Not available|Api et al. 2015; 25636726; 10.1016/j.fct.2015.01.008; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | Relative reliability score | 3 | unitless | Human | Dermal | - | In Vivo; HPPT2020WIP; Human Maximization Test | sheet=Data_invivo; excel_row=4321; Record_ID=skin_sensitization_invivo_1043; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=6.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=Human Maximization Test; Endpoint=Relative reliability score; Response=3; Response_Unit=Unitless; Species=Human; Route=Dermal; Reference=Letizia and Api 2002; Not available; Not available|Api et al. 2015; 25636726; 10.1016/j.fct.2015.01.008|Api et al. 2015; 25430073; 10.3109/15569527.2014.979425; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
| NTP_ICE_skin_sensitization | Relative reliability score | 4 | unitless | Human | Dermal | - | In Vivo; HPPT2020WIP; Human Repeat Insult Patch Test | sheet=Data_invivo; excel_row=4330; Record_ID=skin_sensitization_invivo_1045; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=20.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID8029157; Assay=Human Repeat Insult Patch Test; Endpoint=Relative reliability score; Response=4; Response_Unit=Unitless; Species=Human; Route=Dermal; Reference=RIFM 2001; https://www.rifm.org/rifm-science-database.php#gsc.tab=0|Letizia and Api 2002; Not available; Not available|Basketter et al. 2005; 16283904; 10.1111/j.0105-1873.2005.00707.x|Api et al. 2008; 18406028; 10.1016/j.yrtph.2007.10.008|Natsch et al. 2013; 23576290; 10.1002/jat.2868|Api et al. 2015; 25430073; 10.3109/15569527.2014.979425; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8029157 |
ToxValDB_ECHA_IUCLID 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | NOAEL | =23 | mg/kg bw/day | Rat | oral | chronic; 14 weeks | chronic | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669ead10e4b0a7c65d1c24f0; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/20550/7/6/2?documentUUID=1cc14e7b-191b-4590-9955-a36921719085; YEAR=2005; ORIGINAL_YEAR=2005; STUDY_GROUP=ECHA IUCLID:15850577:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_ba32e7bab1f71e13388dc33cf2ff54d8 |
| ToxValDB_ECHA_IUCLID | NOAEL | =36 | mg/kg bw/day | Rat | oral | chronic; 14 weeks | chronic | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669ead10e4b0a7c65d1c24f0; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/20550/7/6/2?documentUUID=1cc14e7b-191b-4590-9955-a36921719085; YEAR=2005; ORIGINAL_YEAR=2005; STUDY_GROUP=ECHA IUCLID:15850578:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_89ea3217b080847087a57b672f084c11 |
ToxValDB_ECOTOX 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECOTOX | LOEL | =30 | % | Mouse | dermal | short-term; 16 days | short-term | LONG_REF=Contact Dermatitis15(1): 17-23 Maisey,J., and K. Miller Assessment of the Ability of Mice Fed on Vitamin A Supplemented Diet to Respond to a Variety of Potential Contact Sensitizers 1986; TITLE=Assessment of the Ability of Mice Fed on Vitamin A Supplemented Diet to Respond to a Variety of Potential Contact Sensitizers; AUTHOR=Maisey,J., and K. Miller; DOI=10.1111/j.1600-0536.1986.tb01255.x; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=81179; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1986; ORIGINAL_YEAR=1986; TOXICOLOGICAL_EFFECT=Immunological: Thickness; TOXICOLOGICAL_EFFECT_CATEGORY=other; STUDY_GROUP=ECOTOX:15608380:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=c7284af9921ed7271c87d73ad7eb676a |
ToxValDB_EFSA 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_EFSA | NOAEL | =30 | mg/kg bw/day | Rat | oral | chronic; 14 weeks | chronic | LONG_REF=EFSA FEEDAP (2017). Safety and efficacy of aryl-substituted primary alcohol, aldehyde, acid, ester and acetal derivatives belonging to chemical group 22 when used as flavourings for all animal species. doi:10.2903/j.efsa.2017.4672.; TITLE=Safety and efficacy of aryl-substituted primary alcohol, aldehyde, acid, ester and acetal derivatives belonging to chemical group 22 when used as flavourings for all animal species; AUTHOR=EFSA FEEDAP; DOI=doi:10.2903/j.efsa.2017.4672; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/65201d30e4b0f0a60ddd1165; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://zenodo.org/record/5076033#.Y9fEoXbMI2z; YEAR=2017; ORIGINAL_YEAR=2017; TOXICOLOGICAL_EFFECT=organ weight; TOXICOLOGICAL_EFFECT_CATEGORY=organ weight; STUDY_GROUP=EFSA:15621608:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_d3b793c984df49b4b8a81bb0fbe0eca1 |
openFDA substances 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | WC51CA3418 | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"WC51CA3418"} |
| openFDA substances | FDA UNII substance identifier | WC51CA3418 | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"WC51CA3418"} |
| openFDA substances | FDA UNII substance identifier | WC51CA3418 | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"WC51CA3418"} |
| openFDA substances | FDA UNII substance identifier | WC51CA3418 | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"WC51CA3418"} |