Is Ammonium Nitrate safe in cosmetics?
Ammonium Nitrate has a safety rating of "POOR" in our database. EU status: restricted. US status: restricted.
Ammonium Nitrate
Also known as: Divosan MH, NH4NO3, Caswell No. 045, EINECS 229-347-8, EPA Pesticide Chemical Code 076101 (+9 more)
INCI: AMMONIUM NITRATE
Ammonium Nitrate (CAS 6484-52-2) is a cosmetic cosmetic ingredient functioning as Oxidising agent. NOAEL 256 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted; GHS signal word WARNING. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 6484-52-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Ammonium Nitrate is classified GHS Danger (H272, H319, H335) in the chemicals database but is restricted in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Oxidising agent
Safety Rating
POOR
Regulatory Status
EU EU Status
restricted
US US Status
restricted
US Notes
Regulated as an explosive precursor by ATF/DHS; not appropriate for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ammonium Nitrate.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Signal Word
WARNING
Pictograms
Flam circleExcl markWarnCancerHealth haz
Hazard Statements
May intensify fire; oxidizer May be harmful if swallowed Causes skin irritation Causes serious eye irritation May cause damage to blood
Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed.
Routes of Exposure
The substance can be absorbed into the body by inhalation and by ingestion.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Ammonium Nitrate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10,000,000 - 100,000,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Oxidizing agent
pH regulating agent
Regulatory List Membership (2)
EPA Safer Chemical Ingredients List (SCIL)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Ammonium Nitrate.
Regulatory Flags
endocrine_disruptor
epa_safer_alternative
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Ammonium Nitrate by CAS number or substance name.
Studies
12
Lowest NOAEL
256 mg/kg bw/day
Highest NOAEL
1975 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
Divosan MH
NH4NO3
Caswell No. 045
EINECS 229-347-8
EPA Pesticide Chemical Code 076101
Herco prills
Merco Prills
Ammonium nitricum
UNII-T8YA51M7Y6
Ammonium saltpeter
Ammonium(I) nitrate (1:1)
Nitrate of ammonia
Nitrato amonico
Norway saltpeter
Chemical Function
pH regulating agent
Oxidizing agent
Regulatory Lists
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
CEDI
Indirect additives food contact (10/2018)
SCIL (9/2019)
fracking; water
Canada; consumer_product; Substances in Products - Canada (4/2014)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1500032
Frequently Asked Questions
Is Ammonium Nitrate allowed in the EU?
Ammonium Nitrate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ammonium Nitrate do in cosmetics?
Ammonium Nitrate functions as: Oxidising agent. It is classified as a cosmetic ingredient in our database. CAS number: 6484-52-2.
Is Ammonium Nitrate classified as hazardous under GHS?
Ammonium Nitrate carries a GHS signal word of "WARNING". Hazard statements: May intensify fire; oxidizer May be harmful if swallowed Causes skin irritation Causes serious eye irritation May cause damage to blood. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Is Ammonium Nitrate used outside cosmetics?
Ammonium Nitrate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Ammonium Nitrate have different safety status in cosmetics vs industrial chemicals?
Ammonium Nitrate is classified GHS Danger (H272, H319, H335) in the chemicals database but is restricted in EU cosmetics.
Compliance Tools
Check Ammonium Nitrate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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