Is Alpha,3,3-Trimethylcyclohexylmethyl Acetate safe in cosmetics?
Alpha,3,3-Trimethylcyclohexylmethyl Acetate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Alpha,3,3-Trimethylcyclohexylmethyl Acetate
Also known as: Cyclohexane-1-methanol, alpha,3,3-trimethyl-, acetate, EINECS 246-737-3
INCI: ALPHA,3,3-TRIMETHYLCYCLOHEXYLMETHYL ACETATE
Alpha,3,3-Trimethylcyclohexylmethyl Acetate (CAS 25225-10-9) is a cosmetic cosmetic ingredient functioning as Perfuming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 25225-10-9 →
Auto-generated CPSR Part A draft with source citations
Function
Perfuming
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
1-(3,3-dimethylcyclohexyl)ethyl acetate
InChIKey
YWVSYRJWCROMKO-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — IFRA-regulated fragrance ingredient
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Alpha,3,3-Trimethylcyclohexylmethyl Acetate.
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization AOP Dashboard
Adverse Outcome Pathway data across 5 assays (DPRA, KeratinoSens, hCLAT, LLNA, NESIL) aggregated from public sources.
NESIL
2700 µg/cm²
GHS: 1B
Human: positive
Source: HPPT: [122] RIFM (1982): RIFM report number 1643, June 28, unpublished.
HRIPT Human Patch Test Studies
2 human repeat insult patch tests aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2700 | - | - |
| HMT | - | 0 | 6750 | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Alpha,3,3-Trimethylcyclohexylmethyl Acetate.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
Cyclohexane-1-methanol, alpha,3,3-trimethyl-, acetate
EINECS 246-737-3
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
consumer_product
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Alpha,3,3-Trimethylcyclohexylmethyl Acetate allowed in the EU?
Alpha,3,3-Trimethylcyclohexylmethyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Alpha,3,3-Trimethylcyclohexylmethyl Acetate do in cosmetics?
Alpha,3,3-Trimethylcyclohexylmethyl Acetate functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 25225-10-9.
Is Alpha,3,3-Trimethylcyclohexylmethyl Acetate used outside cosmetics?
Alpha,3,3-Trimethylcyclohexylmethyl Acetate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Alpha,3,3-Trimethylcyclohexylmethyl Acetate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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