Is Allyl Propionate safe in cosmetics?
Allyl Propionate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.
Allyl Propionate
Also known as: Allyl propanoate, EINECS 219-307-8, FEMA No. 2040, NSC 7620, 2-Propenyl propanoate (+2 more)
INCI: ALLYL PROPIONATE
Allyl Propionate (CAS 2408-20-0) is a cosmetic cosmetic ingredient functioning as Fragrance. NOAEL 18 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 2408-20-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Allyl Propionate is classified GHS Danger (H226, H301, H315, H319, H335, H311) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Fragrance
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
prop-2-enyl propanoate
InChIKey
XRFWKHVQMACVTA-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically restricted by FDA; governed by general cosmetic safety provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Allyl Propionate.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Allyl Propionate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 19.3 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | =18 mg/kg bw/day | oral | Rat | subchronic | ToxValDB_ECHA_IUCLID |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Allyl Propionate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
Ceased manufacture
Substance Type
SUBSTANCE
SVHC Candidate
No
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (III - Restricted)
BRIN Brazil/India Cosmetics
India: Restricted
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
1
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ALLYL PROPIONATE | 1996 | No safety concern at current levels of intake when used as a flavouring agent | TRS 868-JECFA 46/28
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (4)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Allyl Propionate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
eu_cosing_listed
jecfa_safe
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Allyl Propionate by CAS number or substance name.
Studies
5
Lowest NOAEL
18 mg/kg bw/day
Highest NOAEL
19.3 mg/kg bw/day
COSMOS_DB
ToxValDB_ECHA_IUCLID
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
Allyl propanoate
EINECS 219-307-8
FEMA No. 2040
NSC 7620
2-Propenyl propanoate
Propionic acid, allyl ester
UNII-0OYW8C5029
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe; Personal care; restricted
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Allyl Propionate allowed in the EU?
Allyl Propionate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Allyl Propionate do in cosmetics?
Allyl Propionate functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 2408-20-0.
What is the NOAEL for Allyl Propionate?
The NOAEL (No Observed Adverse Effect Level) for Allyl Propionate is 19.3 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Is Allyl Propionate used outside cosmetics?
Allyl Propionate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Allyl Propionate have different safety status in cosmetics vs industrial chemicals?
Allyl Propionate is classified GHS Danger (H226, H301, H315, H319, H335, H311) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Allyl Propionate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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