Aesculus Hippocastanum Extract

INCI: AESCULUS HIPPOCASTANUM EXTRACT

Aesculus Hippocastanum Extract (CAS 8053-39-2) is a cosmetic active ingredient functioning as Skin conditioning; antioxidant; astringent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 8053-39-2 →

Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning; antioxidant; astringent
Safety Rating
GOOD

Chemistry & Identifiers

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Not FDA restricted; no CIR dedicated assessment; cosmetic use at 0.5-2% well tolerated

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Aesculus Hippocastanum Extract.

Calculate MoS for your specific formulation with the MoS Calculator.

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for Aesculus Hippocastanum Extract.

Regulatory Flags

contact-dermatitis-risk patch-test-recommended botanical-extract no-cir-assessment percutaneous-absorption-documented

Chemical Function

Softener and conditioner Antioxidant Humectant Astringent

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA count match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Adverse Event Associations
673
View full pharmaceutical profile →

Frequently Asked Questions

Is Aesculus Hippocastanum Extract safe in cosmetics?

Aesculus Hippocastanum Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Aesculus Hippocastanum Extract allowed in the EU?

Aesculus Hippocastanum Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aesculus Hippocastanum Extract do in cosmetics?

Aesculus Hippocastanum Extract functions as: Skin conditioning; antioxidant; astringent. It is classified as a Active Ingredient in our database. CAS number: 8053-39-2.

Is Aesculus Hippocastanum Extract used outside cosmetics?

Aesculus Hippocastanum Extract also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good Similar safety
Antioxidant
Aesculus Hippocastanum Bark Extract
Good Chemical family
Skin Conditioning, Astringent, Anti-i...
Aesculus Hippocastanum Bud Extract
Good Chemical family
Skin Conditioning
Aesculus Hippocastanum Flower Extract
Moderate Chemical family
Softener and conditioner

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