Is Acetylbenzofuran safe in cosmetics?
Acetylbenzofuran has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
Acetylbenzofuran
Also known as: 5-17-10-00172, 2-Acetylcoumarone, 2-Acetylcumarone, Benzo(b)furan-2-yl methyl ketone, 2-Benzofuranyl methyl ketone (+6 more)
INCI: ACETYLBENZOFURAN
Acetylbenzofuran (CAS 1646-26-0) is a cosmetic cosmetic ingredient functioning as Masking, Perfuming. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 1646-26-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Acetylbenzofuran is prohibited in EU cosmetics but has active industrial GHS classifications (H317).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Masking, Perfuming
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
1-(1-benzofuran-2-yl)ethanone
InChIKey
YUTFQTAITWWGFH-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Not restricted by FDA; no CIR review published
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Acetylbenzofuran.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for Acetylbenzofuran.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
Known Synonyms
5-17-10-00172
2-Acetylcoumarone
2-Acetylcumarone
Benzo(b)furan-2-yl methyl ketone
2-Benzofuranyl methyl ketone
1-(2-Benzofuranyl)ethanone
BRN 0117910
EINECS 216-706-9
NSC 23974
NSC 28904
UNII-A1FJQ7D0K3
Chemical Function
Deodorizer
Fragrance
Regulatory Lists
IFRA Transparency
Australian Status
AICIS status: listed_with_terms
Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the importation volume exceeds one tonne per annum...
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL561390
Frequently Asked Questions
Is Acetylbenzofuran allowed in the EU?
Acetylbenzofuran EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetylbenzofuran do in cosmetics?
Acetylbenzofuran functions as: Masking, Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 1646-26-0.
Is Acetylbenzofuran used outside cosmetics?
Acetylbenzofuran also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Acetylbenzofuran have different safety status in cosmetics vs industrial chemicals?
Acetylbenzofuran is prohibited in EU cosmetics but has active industrial GHS classifications (H317).
Compliance Tools
Check Acetylbenzofuran compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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ACETOBACTER FERMENT EXTRACT FILTRATE
Good
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ACETOBACTER/ASPERGILLUS/LACTOBACILLUS/LEUCONOSTOC/PEDIOCOCCUS/SACCHAROMYCES/ZYGOSACCHAROMYCES/CITRUS UNSHIU FRUIT/CITRUS JAPONICA FRUIT/CITRUS JUNOS FRUIT/ APPLE FRUIT/BANANA FRUIT/PAPAYA FRUIT/ PYRUS SEROTINA FRUIT/ DIOSPYROS KAKI FRUIT/WATERMELON FRUIT/PEACH FRUIT/ PRUNUS MUME FRUIT/FIG FRUIT/CHAENOMELES SINENSIS FRUIT/ERIOBOTRYA JAPONICA FRUIT/APRICOT FRUIT/ ZIZYPHUS JUJUBA FRUIT/CUCURBITA MAXIMA FRUIT/CASTANEA CRENATA FRUIT/VITIS COIGNETIAE FRUIT/RASPBERRY FRUIT/MOMORDICA GROSVENORII FRUIT/LYCIUM CHINENSE FRUIT/GLYCINE MAX SEED/PHASEOLUS ANGULARIS SEED/CANAVALIA ENSIFORMIS SEED/RICE SEED/HORDEUM VULGARE SEED/COIX LACRYMA-JOBI MA-YUEN SEED/ECHINOCHLOA CRUS-GALLI SEED/SETARIA ITALICA SEED/MILLET SEED/HEMEROCALLIS FULVA FLOWER/CABBAGE LEAF/STEM/MORUS BOMBYCIS LEAF/PERILLA FRUTESCENS LEAF/IPOMOEA BATATAS ROOT/COLOCASIA ANTIQUORUM TUBER/DIOSCOREA BATATAS RHIZOME/IRIDEA LAMINARIOIDES/LAMINARIA JAPONICA/NEMACYSTUS DECIPIENS/UNDARIA PINNATIFIDA/RADISH ROOT/TURNIP ROOT/CARROT ROOT/ARCTIUM LAPPA ROOT/NELUMBO NUCIFERA RHIZOME/ONION BULB/LILIUM AURATUM BULB/LICORICE ROOT/SAGITTARIA TRIFOLIA ROOT/SESAME SEED/GINKGO BILOBA SEED/JUGLANS SUBCORDIFORMIS FRUIT/PANAX GINSENG SEED/ACTINIDIA POLYGAMA FRUIT/HYDNUM ERINACEUM FRUITING BODY/GRIFOLA FRONDOSA FRUITING BODY/PRUNUS SALICINA FRUIT/AKEBIA QUINATA FRUIT/CRATAEGUS CUNEATA FRUIT/CORNUS OFFICINALIS FRUIT/NEPHELIUM LONGANA FRUIT/HOUTTUYNIA CORDATA/ARTEMISIA PRINCEPS/SASA VEITCHII LEAF/GLECHOMA HEDERACEA/CHAMOMILLA RECUTITA FLOWER/EQUISETUM ARVENSE/CASSIA OBTUSIFOLIA SEED/TARAXACUM OFFICINALE/ISODON JAPONICUS/SAFFLOWER FLOWER/PLANTAGO ASIATICA/SMALLANTHUS SONCHIFOLIUS ROOT/GARLIC BULB/GINGER RHIZOME/BEET RHIZOME/POLYGONUM ODORATUM RHIZOME/TURMERIC RHIZOME/ACANTHOPANAX SIEBOLDIANUS ROOT/PINUS KORAIENSIS SEED/LENTINUS EDODES FRUITING BODY/AURICULARIA AURICULA/VITIS LABRUSCA FRUIT/HELIANTHUS TUBEROSUS TUBER FERMENT EXTRACT
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