Is 7-Dehydrocholesterol safe in cosmetics?
7-Dehydrocholesterol has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
7-Dehydrocholesterol
Also known as: Cholesta-5,7-dien-3-ol, (3β)-, Cholesta-5,7-dien-3β-ol, (3β)-Cholesta-5,7-dien-3-ol, 7-Dehydrocholesterin, Cholesterol, 7-dehydro- (+14 more)
INCI: 7-DEHYDROCHOLESTEROL
7-Dehydrocholesterol (CAS 434-16-2) is a cosmetic cosmetic ingredient functioning as Emulsion stabilising, Skin conditioning, Viscosity controlling. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 434-16-2 →
Auto-generated CPSR Part A draft with source citations
Function
Emulsion stabilising, Skin conditioning, Viscosity controlling
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR Final Report 2023 — safe as used in cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 7-Dehydrocholesterol.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Softener and conditioner
Thickening agent
Viscosity modifier
Expert Verdict
Expert safety assessment and concern-level summary for 7-Dehydrocholesterol.
Known Synonyms
Cholesta-5,7-dien-3-ol, (3β)-
Cholesta-5,7-dien-3β-ol
(3β)-Cholesta-5,7-dien-3-ol
7-Dehydrocholesterin
Cholesterol, 7-dehydro-
Dehydrocholesterol
Provitamin D3
Δ5,7-Cholestadien-3β-ol
Δ7-Cholesterol
7,8-didehidrocolesterol
(3b)-Cholesta-5,7-dien-3-ol
Cholesta-5,7-dien-3-ol, (3beta)-
Cholesta-5,7-dien-3-ol, (3.beta.)-
NSC 18159
(-)-7-dehydrocholesterol
(1S,2R,5S,11R,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.02,7.011,15]heptadeca-7,9-dien-5-ol
(3beta)-cholesta-5,7-dien-3-ol
10,13-Dimethyl-17-(6-methylheptan-2-yl)-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
17-(1,5-Dimethylhexyl)-10,13-dimethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Chemical Function
Softener and conditioner
Viscosity modifier
Emulsifier
Thickening agent
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1797131
Frequently Asked Questions
Is 7-Dehydrocholesterol allowed in the EU?
7-Dehydrocholesterol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 7-Dehydrocholesterol do in cosmetics?
7-Dehydrocholesterol functions as: Emulsion stabilising, Skin conditioning, Viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 434-16-2.
Is 7-Dehydrocholesterol used outside cosmetics?
7-Dehydrocholesterol also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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