What is the NOAEL for 7,8-Didehydrocholesterol?
7,8-Didehydrocholesterol has 4 NOAEL studies in the database. The lowest reported value is BK1IU07GKF UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
7,8-Didehydrocholesterol
Also known as: Cholesta-5,7-dien-3-ol, (3β)-, Cholesta-5,7-dien-3β-ol, (3β)-Cholesta-5,7-dien-3-ol, 7-Dehydrocholesterin, 7-Dehydrocholesterol (+15 more)
CAS 434-16-2
7,8-Didehydrocholesterol (CAS 434-16-2) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
7,8-Didehydrocholesterol
CAS Number
434-16-2
DTXSID
DTXSID20861933
Molecular Formula
C27H44O
InChI Key
UCTLRSWJYQTBFZ-DDPQNLDTSA-N
Monoisotopic Mass
384.339216
Synonyms
Cholesta-5,7-dien-3-ol, (3β)-Cholesta-5,7-dien-3β-ol(3β)-Cholesta-5,7-dien-3-ol7-Dehydrocholesterin7-DehydrocholesterolCholesterol, 7-dehydro-DehydrocholesterolProvitamin D3Δ5,7-Cholestadien-3β-olΔ7-Cholesterol7,8-didehidrocolesterol(3b)-Cholesta-5,7-dien-3-ol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
8 records
Softener and conditionerViscosity modifierEmulsifierThickening agent
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| BK1IU07GKF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BK1IU07GKF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BK1IU07GKF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BK1IU07GKF | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 7,8-didehydrocholesterol | 207-100-5 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Rheology Modifier
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1797131
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
Is 7,8-Didehydrocholesterol used in cosmetics?
Yes, 7,8-Didehydrocholesterol is also indexed as a cosmetic ingredient under the name 7-Dehydrocholesterol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 7,8-Didehydrocholesterol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 7,8-Didehydrocholesterol used outside industrial chemicals?
7,8-Didehydrocholesterol also appears in cosmetics, pharmaceutical databases.