Is 5-Amino-2,6-Dimethoxy-3-Hydroxypyridine safe in cosmetics?
5-Amino-2,6-Dimethoxy-3-Hydroxypyridine has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
5-Amino-2,6-Dimethoxy-3-Hydroxypyridine
Also known as: UNII-84VZY2W96H, 3-Amino-5-hydroxy-2,6-dimethoxypyridine, 3-Pyridinol, 5-amino-2,6-dimethoxy-
INCI: 5-AMINO-2,6-DIMETHOXY-3-HYDROXYPYRIDINE
5-Amino-2,6-Dimethoxy-3-Hydroxypyridine (CAS 104333-03-1) is a cosmetic cosmetic ingredient functioning as Hair dye (oxidative and non-oxidative systems). EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 104333-03-1 →
Auto-generated CPSR Part A draft with source citations
Function
Hair dye (oxidative and non-oxidative systems)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Permitted for hair dye use; not separately listed under FDA coal-tar hair dye provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 5-Amino-2,6-Dimethoxy-3-Hydroxypyridine.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1308
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1308
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for 5-Amino-2,6-Dimethoxy-3-Hydroxypyridine.
Regulatory Flags
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
UNII-84VZY2W96H
3-Amino-5-hydroxy-2,6-dimethoxypyridine
3-Pyridinol, 5-amino-2,6-dimethoxy-
Chemical Function
Dye
Regulatory Lists
banned; Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 5-Amino-2,6-Dimethoxy-3-Hydroxypyridine allowed in the EU?
5-Amino-2,6-Dimethoxy-3-Hydroxypyridine EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does 5-Amino-2,6-Dimethoxy-3-Hydroxypyridine do in cosmetics?
5-Amino-2,6-Dimethoxy-3-Hydroxypyridine functions as: Hair dye (oxidative and non-oxidative systems). It is classified as a cosmetic ingredient in our database. CAS number: 104333-03-1.
Compliance Tools
Check 5-Amino-2,6-Dimethoxy-3-Hydroxypyridine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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