Is 3-O-Cetyl Ascorbic Acid safe in cosmetics?
3-O-Cetyl Ascorbic Acid has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
3-O-Cetyl Ascorbic Acid
Also known as: UNII-L0VNO92L8V, 3-O-Hexadecyl-L-ascorbic acid, l-Ascorbic acid, 3-O-hexadecyl-, Nikkol VCE
INCI: 3-O-CETYL ASCORBIC ACID
3-O-Cetyl Ascorbic Acid (CAS 88306-70-1) is a cosmetic cosmetic ingredient functioning as Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 88306-70-1 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hexadecoxy-4-hydroxy-2H-furan-5-one
InChIKey
SQYJRUFNBSYSAI-AZUAARDMSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific FDA restriction; falls under general cosmetic ingredient provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 3-O-Cetyl Ascorbic Acid.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for 3-O-Cetyl Ascorbic Acid.
Known Synonyms
UNII-L0VNO92L8V
3-O-Hexadecyl-L-ascorbic acid
l-Ascorbic acid, 3-O-hexadecyl-
Nikkol VCE
Chemical Function
Softener and conditioner
Frequently Asked Questions
Is 3-O-Cetyl Ascorbic Acid allowed in the EU?
3-O-Cetyl Ascorbic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 3-O-Cetyl Ascorbic Acid do in cosmetics?
3-O-Cetyl Ascorbic Acid functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 88306-70-1.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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