Is 3-Ethyl-2,5-Dimethylpyrazine safe in cosmetics?
3-Ethyl-2,5-Dimethylpyrazine has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
3-Ethyl-2,5-Dimethylpyrazine
Also known as: Pyrazine, 3-ethyl-2,5-dimethyl-, 2-Ethyl-3,6-dimethylpyrazine, 3,6-Dimethyl-2-ethylpyrazine, EC No.: 236-417-1, EINECS 236-417-1 (+1 more)
INCI: 3-ETHYL-2,5-DIMETHYLPYRAZINE
3-Ethyl-2,5-Dimethylpyrazine (CAS 13360-65-1) is a cosmetic cosmetic ingredient functioning as Perfuming — nutty, roasted character. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 13360-65-1 →
Auto-generated CPSR Part A draft with source citations
Function
Perfuming — nutty, roasted character
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3-ethyl-2,5-dimethylpyrazine
InChIKey
WHMWOHBXYIZFPF-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; also GRAS (Generally Recognized As Safe) as a food flavoring agent
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 3-Ethyl-2,5-Dimethylpyrazine.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for 3-Ethyl-2,5-Dimethylpyrazine.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
Pyrazine, 3-ethyl-2,5-dimethyl-
2-Ethyl-3,6-dimethylpyrazine
3,6-Dimethyl-2-ethylpyrazine
EC No.: 236-417-1
EINECS 236-417-1
UNII-G2FB13VLOG
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL95123
Frequently Asked Questions
Is 3-Ethyl-2,5-Dimethylpyrazine allowed in the EU?
3-Ethyl-2,5-Dimethylpyrazine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 3-Ethyl-2,5-Dimethylpyrazine do in cosmetics?
3-Ethyl-2,5-Dimethylpyrazine functions as: Perfuming — nutty, roasted character. It is classified as a cosmetic ingredient in our database. CAS number: 13360-65-1.
Is 3-Ethyl-2,5-Dimethylpyrazine used outside cosmetics?
3-Ethyl-2,5-Dimethylpyrazine also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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