Is 2,4-Dimethyl-4-phenyltetrahydrofuran safe in cosmetics?
2,4-Dimethyl-4-phenyltetrahydrofuran has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
2,4-Dimethyl-4-phenyltetrahydrofuran
INCI: 2,4-DIMETHYL-4-PHENYLTETRAHYDROFURAN
2,4-Dimethyl-4-phenyltetrahydrofuran (CAS 82461-14-1 (also 99343-90-5 for (2R,4R)-rel isomer)) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming agent); also known as Rhubafurane. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
82461-14-1 (also 99343-90-5 for (2R,4R)-rel isomer)
View industrial chemical safety profile →
Function
Fragrance (perfuming agent); also known as Rhubafurane
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted as fragrance ingredient; also evaluated as synthetic flavoring substance
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2,4-Dimethyl-4-phenyltetrahydrofuran.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for 2,4-Dimethyl-4-phenyltetrahydrofuran.
Regulatory Flags
fragrance-component
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to 2,4-Dimethyl-4-phenyltetrahydrofuran by CAS number or substance name.
Studies
6
Lowest NOAEL
200 mg/kg bw/day
Highest NOAEL
600 mg/kg bw/day
ECHA
Frequently Asked Questions
Is 2,4-Dimethyl-4-phenyltetrahydrofuran allowed in the EU?
2,4-Dimethyl-4-phenyltetrahydrofuran EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2,4-Dimethyl-4-phenyltetrahydrofuran do in cosmetics?
2,4-Dimethyl-4-phenyltetrahydrofuran functions as: Fragrance (perfuming agent); also known as Rhubafurane. It is classified as a cosmetic ingredient in our database. CAS number: 82461-14-1 (also 99343-90-5 for (2R,4R)-rel isomer).
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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