Is 2,3-Diethylpyrazine safe in cosmetics?
2,3-Diethylpyrazine has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
2,3-Diethylpyrazine
Also known as: Pyrazine, 2,3-diethyl-, EINECS 239-800-1, FEMA No. 3136, UNII-AD31A42VY0
INCI: 2,3-DIETHYLPYRAZINE
2,3-Diethylpyrazine (CAS 15707-24-1) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient (nutty, roasted, cocoa aroma). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 15707-24-1 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient (nutty, roasted, cocoa aroma)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2,3-diethylpyrazine
InChIKey
GZXXANJCCWGCSV-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted; FEMA GRAS status for food use supports safety profile
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2,3-Diethylpyrazine.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
771
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
2,3-DIETHYLPYRAZINE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/51 | FAS 48-JECFA 57/135
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for 2,3-Diethylpyrazine.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
Pyrazine, 2,3-diethyl-
EINECS 239-800-1
FEMA No. 3136
UNII-AD31A42VY0
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL327303
Frequently Asked Questions
Is 2,3-Diethylpyrazine allowed in the EU?
2,3-Diethylpyrazine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2,3-Diethylpyrazine do in cosmetics?
2,3-Diethylpyrazine functions as: Fragrance ingredient (nutty, roasted, cocoa aroma). It is classified as a cosmetic ingredient in our database. CAS number: 15707-24-1.
Is 2,3-Diethylpyrazine used outside cosmetics?
2,3-Diethylpyrazine also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 2,3-Diethylpyrazine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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