Is 2,2'-Methylenebis 4-Aminophenol safe in cosmetics?
2,2'-Methylenebis 4-Aminophenol has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
2,2'-Methylenebis 4-Aminophenol
INCI: 2,2'-METHYLENEBIS 4-AMINOPHENOL
2,2'-Methylenebis 4-Aminophenol (CAS 63969-46-0 (free base)) is a cosmetic cosmetic ingredient functioning as Hair dyeing - oxidation hair colorant (permanent hair dyes). EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 63969-46-0 (free base) →
Auto-generated CPSR Part A draft with source citations
Function
Hair dyeing - oxidation hair colorant (permanent hair dyes)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Coal tar hair dye exemption applies; subject to FDA labeling requirements (caution statement + patch test)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2,2'-Methylenebis 4-Aminophenol.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for 2,2'-Methylenebis 4-Aminophenol.
Regulatory Flags
potential-allergen
colorant
Frequently Asked Questions
Is 2,2'-Methylenebis 4-Aminophenol allowed in the EU?
2,2'-Methylenebis 4-Aminophenol EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2,2'-Methylenebis 4-Aminophenol do in cosmetics?
2,2'-Methylenebis 4-Aminophenol functions as: Hair dyeing - oxidation hair colorant (permanent hair dyes). It is classified as a cosmetic ingredient in our database. CAS number: 63969-46-0 (free base).
Compliance Tools
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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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2,2'-METHYLENEBIS-4-AMINOPHENOL
Good
Chemical family
Hair Dyeing
2,2'-Methylenebis-4-Aminophenol HCl
Moderate
Browse nearby
Hair dyeing - oxidative and non-oxida...
2,2'-Thiobis(4-Chlorophenol)
Poor
Browse nearby
Antimicrobial / antifungal agent
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