Is 2-Tert-Butylcyclohexanone safe in cosmetics?
2-Tert-Butylcyclohexanone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
2-Tert-Butylcyclohexanone
Also known as: Cyclohexanone, 2-(1,1-dimethylethyl)-, EINECS 217-043-8, ortho-tert-Butylcyclohexanone
INCI: 2-TERT-BUTYLCYCLOHEXANONE
2-Tert-Butylcyclohexanone (CAS 1728-46-7) is a cosmetic cosmetic ingredient functioning as Perfuming (fragrance). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 1728-46-7 →
Auto-generated CPSR Part A draft with source citations
Function
Perfuming (fragrance)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-tert-butylcyclohexan-1-one
InChIKey
ZRYDPLOWJSFQAE-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no FDA cosmetic restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2-Tert-Butylcyclohexanone.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for 2-Tert-Butylcyclohexanone.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
Cyclohexanone, 2-(1,1-dimethylethyl)-
EINECS 217-043-8
ortho-tert-Butylcyclohexanone
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3183402
Frequently Asked Questions
Is 2-Tert-Butylcyclohexanone allowed in the EU?
2-Tert-Butylcyclohexanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Tert-Butylcyclohexanone do in cosmetics?
2-Tert-Butylcyclohexanone functions as: Perfuming (fragrance). It is classified as a cosmetic ingredient in our database. CAS number: 1728-46-7.
Is 2-Tert-Butylcyclohexanone used outside cosmetics?
2-Tert-Butylcyclohexanone also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 2-Tert-Butylcyclohexanone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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