Is 2-Pentanol safe in cosmetics?
2-Pentanol has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
2-Pentanol
Also known as: 4-01-00-01656, BRN 1718819, EINECS 227-907-6, FEMA No. 3316, Pentanol, sec- (+15 more)
INCI: 2-PENTANOL
2-Pentanol (CAS 6032-29-7) is a cosmetic cosmetic ingredient functioning as Perfuming, solvent. EU Regulation 1223/2009 status: permitted; GHS signal word WARNING. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 6032-29-7 →
Auto-generated CPSR Part A draft with source citations
Function
Perfuming, solvent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
pentan-2-ol
InChIKey
JYVLIDXNZAXMDK-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA restriction; GRAS for flavoring; permitted in cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2-Pentanol.
Calculate MoS for your specific formulation with the MoS Calculator.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Signal Word
WARNING
Pictograms
FlamFlameExcl markWarnCancerHealth haz
Hazard Statements
Flammable liquid and vapour Harmful if swallowed Causes eye irritation May cause respiratory irritation May cause drowsiness or dizziness May be harmful if swallowed and enters airways
Short-term Exposure Effects
The substance is irritating to the eyes and respiratory tract. If swallowed the substance may cause vomiting and could result in aspiration pneumonitis. The substance may cause effects on the central nervous system. Exposure at high levels could cause lowering of consciousness.
Long-term Exposure Effects
Repeated or prolonged contact with skin may cause dermatitis.
Routes of Exposure
The substance can be absorbed into the body by inhalation and by ingestion.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
ICSC Safety Card
1428
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Regulatory (3)
JECFA Number
280
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
2-PENTANOL | 1998 | No safety concern at current levels of intake when used as a flavouring agent | TRS 891-JECFA 51/59 | FAS 42-JECFA 51/235
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
sec-AMYL ALCOHOL | 1998 | No safety concern at current levels of intake when used as a flavouring agent | TRS 891-JECFA 51/59 | FAS 42-JECFA 51/235
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for 2-Pentanol.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
4-01-00-01656
BRN 1718819
EINECS 227-907-6
FEMA No. 3316
Pentanol, sec-
UNII-04G7050365
(+/-)-2-Pentanol
(R)-(-)-2-Pentanol
(S)-(+)-2-pentanol
FEMA 3316
Isoamyl alcohol (primary/secondary
Isoamyl alcohol, secondary
Methyl butanol
Methyl propyl carbinol
Methyl-Butanol
Methylbutan-1-ol
Pentanol-2
Sec-pentanol
alpha-Methylbutanol
n-C3H7CH(OH)CH3
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
2-PENTANOL
ChEMBL ID
CHEMBL45065
Frequently Asked Questions
Is 2-Pentanol allowed in the EU?
2-Pentanol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Pentanol do in cosmetics?
2-Pentanol functions as: Perfuming, solvent. It is classified as a cosmetic ingredient in our database. CAS number: 6032-29-7.
Is 2-Pentanol classified as hazardous under GHS?
2-Pentanol carries a GHS signal word of "WARNING". Hazard statements: Flammable liquid and vapour Harmful if swallowed Causes eye irritation May cause respiratory irritation May cause drowsiness or dizziness May be harmful if swallowed and enters airways. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Is 2-Pentanol used outside cosmetics?
2-Pentanol also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 2-Pentanol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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