Is 2-Methoxy-3-Methylpyrazine safe in cosmetics?
2-Methoxy-3-Methylpyrazine has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
2-Methoxy-3-Methylpyrazine
Also known as: Pyrazine, 2-methoxy-3-methyl-, 2-Methyl-3-methoxypyrazine, 3-Methoxy-2-methylpyrazine, EINECS No.: 220-651-6
INCI: 2-METHOXY-3-METHYLPYRAZINE
2-Methoxy-3-Methylpyrazine (CAS 2847-30-5) is a cosmetic cosmetic ingredient functioning as Fragrance — earthy, roasted, green-pepper aroma. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 2847-30-5 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance — earthy, roasted, green-pepper aroma
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-methoxy-3-methylpyrazine
InChIKey
VKJIAEQRKBQLLA-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — also used as a flavor ingredient; no FDA cosmetic prohibition
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2-Methoxy-3-Methylpyrazine.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for 2-Methoxy-3-Methylpyrazine.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
Pyrazine, 2-methoxy-3-methyl-
2-Methyl-3-methoxypyrazine
3-Methoxy-2-methylpyrazine
EINECS No.: 220-651-6
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL329881
Frequently Asked Questions
Is 2-Methoxy-3-Methylpyrazine allowed in the EU?
2-Methoxy-3-Methylpyrazine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Methoxy-3-Methylpyrazine do in cosmetics?
2-Methoxy-3-Methylpyrazine functions as: Fragrance — earthy, roasted, green-pepper aroma. It is classified as a cosmetic ingredient in our database. CAS number: 2847-30-5.
Is 2-Methoxy-3-Methylpyrazine used outside cosmetics?
2-Methoxy-3-Methylpyrazine also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 2-Methoxy-3-Methylpyrazine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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