Is 2-Amino-3-Nitrophenol safe in cosmetics?
2-Amino-3-Nitrophenol has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
2-Amino-3-Nitrophenol
Also known as: 3-Nitro-2-aminophenol, 1-Hydroxy-2-amino-3-nitrobenzene, Phenol, 2-amino-3-nitro-, 2-Amino-3-hydroxynitrobenzene, 2-Hydroxy-6-nitroaniline (+2 more)
INCI: 2-AMINO-3-NITROPHENOL
2-Amino-3-Nitrophenol (CAS 603-85-0) is a cosmetic cosmetic ingredient functioning as Hair dyeing (semi-permanent / non-oxidative dye coupler). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 603-85-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
2-Amino-3-Nitrophenol is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H335).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Hair dyeing (semi-permanent / non-oxidative dye coupler)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-amino-3-nitrophenol
InChIKey
KUCWUAFNGCMZDB-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
CIR concluded safe as a hair dye ingredient in current practices of use and concentration
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2-Amino-3-Nitrophenol.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1317
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1317
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for 2-Amino-3-Nitrophenol.
Regulatory Flags
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
3-Nitro-2-aminophenol
1-Hydroxy-2-amino-3-nitrobenzene
Phenol, 2-amino-3-nitro-
2-Amino-3-hydroxynitrobenzene
2-Hydroxy-6-nitroaniline
EINECS 210-060-1
UNII-A7F97ZPU2W
Chemical Function
Dye
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
banned; Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 2-Amino-3-Nitrophenol allowed in the EU?
2-Amino-3-Nitrophenol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Amino-3-Nitrophenol do in cosmetics?
2-Amino-3-Nitrophenol functions as: Hair dyeing (semi-permanent / non-oxidative dye coupler). It is classified as a cosmetic ingredient in our database. CAS number: 603-85-0.
Is 2-Amino-3-Nitrophenol used outside cosmetics?
2-Amino-3-Nitrophenol also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does 2-Amino-3-Nitrophenol have different safety status in cosmetics vs industrial chemicals?
2-Amino-3-Nitrophenol is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H335).
Compliance Tools
Check 2-Amino-3-Nitrophenol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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