Food Safety Substance
Papain
Papain is a food additive with Not listed as EU additive (processing aid) in the EU, GRAS in the US, and data from 6 regulatory sources.
Substance Identity
Resolved identifiers used to render this food-safety record.
Multi-Jurisdiction Comparison
Side-by-side status rows for the same resolved substance across public food regulators.
| Jurisdiction | Authority | Status | Evidence |
|---|---|---|---|
| European Union | EU Commission | Not listed as EU additive (processing aid) | - |
| Canada | Health Canada | Listed | Food enzyme |
| Codex | Codex Alimentarius | Listed | Flavour enhancer |
Codex GSFA Status
Codex Alimentarius GSFA permissions and maximum-use rows.
| Jurisdiction | INS / E-number | Function | Food category | Max level | Notes |
|---|---|---|---|---|---|
| Codex | 1101(ii) | Flavour enhancer | Table 3 Foods in General (GMP) | GMP | Table 3 additive - GMP in foods in general |
Health Canada Status
Health Canada food-additive permissions by functional class and food scope.
| Jurisdiction | Class | Permitted foods | Maximum level | List |
|---|---|---|---|---|
| Canada | Food enzyme | (a) Beef | (a) Good Manufacturing Practice. To be used before slaughter. | List of Permitted Food Enzymes |
| Canada | Food enzyme | (b) Beer | (b) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (c) Cuts of prepared meat; Cuts of prepared poultry meat | (c) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (d) Hydrolyzed animal, milk, and vegetable proteins | (d) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (e) Meat tenderizing preparations | (e) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (f) Pre-cooked (instant) breakfast cereals | (f) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (g) Pumping pickle used in the curing of beef cuts | (g) Good Manufacturing Practice. In accordance with subsection B.16.019(1) of the Food and Drug Regulations . | List of Permitted Food Enzymes |
| Canada | Food enzyme | (h) Sausage casings; Water-soluble edible collagen films | (h) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (i) Unstandardized bakery products | (i) Good Manufacturing Practice | List of Permitted Food Enzymes |
JECFA ADI Values
JECFA ADI records and evaluation years.
| Jurisdiction | Chemical name | JECFA no. | CAS | ADI | ADI upper | Function | Evaluation year |
|---|---|---|---|---|---|---|---|
| JECFA | PAPAIN | - | 9001-73-4(PAPAIN);9001-09-6(CHYMOPAPAIN) | NOT LIMITED | - | ENZYME_PREPARATION | 1971 |
Cross-Reference to Cosmetics / Chemicals / Pharma
Same-CAS public rows from adjacent Roots verticals where available.
Cross-Vertical Regulatory Divergence
This substance has different regulatory treatment across food, cosmetics, and industrial use.
Frequently Asked Questions
Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.
What is Papain used for in food?
Papain appears in food-use rows as: stabilizer; Flavour enhancer; Food enzyme.
Is Papain safe?
This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: ADI NOT LIMITED mg/kg bw. EU status evidence: Not listed as EU additive (processing aid). US/FDA evidence: GRAS.
What is the ADI for Papain?
Papain has this ADI/reference value in the food-safety tables: ADI NOT LIMITED mg/kg bw. Source: WHO/JECFA.
Is Papain also used in cosmetics?
Papain has a same-CAS cosmetics cross-reference: Papain, EU status permitted.