What is the NOAEL for D-Trehalose?
D-Trehalose has 4 NOAEL studies in the database. The lowest reported value is B8WCK70T7I UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
D-Trehalose
Also known as: Trehalose, Cabaletta, O-D-Glucopyranosyl-(1→1)-D-glucopyranoside, Thealoz, Treha (+14 more)
CAS 99-20-7
D-Trehalose (CAS 99-20-7) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
D-Trehalose
CAS Number
99-20-7
DTXSID
DTXSID3048102
Molecular Formula
C12H22O11
InChI Key
HDTRYLNUVZCQOY-LIZSDCNHSA-N
Monoisotopic Mass
342.116212
Synonyms
TrehaloseCabalettaO-D-Glucopyranosyl-(1→1)-D-glucopyranosideThealozTrehaTrehalose 100PHTrehaose.alpha.-D-Glucopyranoside, .alpha.-D-glucopyranosylalpha-D-Glucopyranoside, alpha-D-glucopyranosylEINECS 202-739-6UNII-B8WCK70T7I(2R,3R,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-oxane-3,4,5-triol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
38 records
HumectantFlavouring and nutrientSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| B8WCK70T7I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B8WCK70T7I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B8WCK70T7I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B8WCK70T7I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Trehalose | 202-739-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
humectant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
TREHALOSE
ChEMBL Phase
3
Adverse Events
1
Bioactivity
2
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
2 records
ADI: NOT SPECIFIED mg/kg bw | FDA GRAS: FDA has no questions
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include D-Trehalose?
D-Trehalose appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is D-Trehalose used in cosmetics?
Yes, D-Trehalose is also indexed as a cosmetic ingredient under the name Trehalose. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for D-Trehalose come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is D-Trehalose used outside industrial chemicals?
D-Trehalose also appears in cosmetics, pharmaceutical, food safety, cannabis databases.