What is the NOAEL for Alpha-Methylbenzyl alcohol?
Alpha-Methylbenzyl alcohol has 36 NOAEL studies in the database. The lowest reported value is 0.1 mg/kg via oral in Human. Source: ToxValDB_WHO_JECFA_ADI.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Alpha-Methylbenzyl alcohol
Also known as: 1-Phenylethanol (alpha-Methylbenzyl alcohol) (Benzenemethanol, .alpha.-methyl-), Benzenemethanol, .alpha.-methyl-, Benzenemethanol, alpha-methyl-, EINECS 202-707-1, EINECS 236-361-8 (+15 more)
CAS 98-85-1
Alpha-Methylbenzyl alcohol (CAS 98-85-1) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Alpha-Methylbenzyl alcohol is classified GHS Danger (H302, H319, H315, H318, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
36
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Alpha-Methylbenzyl alcohol
CAS Number
98-85-1
DTXSID
DTXSID1020859
Molecular Formula
C8H10O
InChI Key
WAPNOHKVXSQRPX-UHFFFAOYSA-N
Monoisotopic Mass
122.073165
Synonyms
1-Phenylethanol (alpha-Methylbenzyl alcohol) (Benzenemethanol, .alpha.-methyl-)Benzenemethanol, .alpha.-methyl-Benzenemethanol, alpha-methyl-EINECS 202-707-1EINECS 236-361-8FEMA No. 2685FEMA Number 2685Methanol, methylphenyl-NCI-C556851-FenylethanolFenyl-methylkarbinolUNII-E6O895DQ52
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| Cleaning products and household care - air freshener; Europe | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 36 of 36 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| <=0.1 | mg/kg | ADI | oral | Human | ToxValDB_WHO_JECFA_ADI |
| =0.1 | mg/kg bw/day | ADI | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =0.1 | mg/kg bw/day | ADI | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =4.66 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| E6O895DQ52 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E6O895DQ52 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E6O895DQ52 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E6O895DQ52 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 5184 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =400 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =46.9 | mg/kg bw/day | LOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| =93 | mg/kg bw/day | LOAEL | oral: gavage | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =93 | mg/kg bw/day | LOAEL | oral: gavage | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =187.5 | mg/kg bw/day | LOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| =375 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =508 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =750 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =1400 | mg/kg bw/day | LOAEL | dermal | Rat | ToxValDB_ECHA_IUCLID |
| =43 | mg/kg bw/day | NOAEL | dermal | Rat | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =50 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =50 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =70 | mg/kg bw/day | NOAEL | dermal | Rat | ToxValDB_ECHA_IUCLID |
| 93 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =93 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =140 | mg/kg bw/day | NOAEL | dermal | Rat | ToxValDB_ECHA_IUCLID |
| 375 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| =430 | mg/kg bw/day | NOAEL | dermal | Rat | ToxValDB_ECHA_IUCLID |
| =500 | mg/kg bw/day | NOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| 750 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 1000 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 2000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
| 750 | mg/kg bw/day | Top dose | Gavage | Mouse | NTP_ICE_cancer |
Showing 36 of 36 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 1-phenylethanol | 202-707-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
PHENYL ETHANOL
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Alpha-Methylbenzyl alcohol?
Alpha-Methylbenzyl alcohol appears on 5 regulatory/inventory lists including Europe, Cleaning products and household care - air freshener; Europe, IFRA Transparency, and 2 more. Source: EPA CPDat.
Is Alpha-Methylbenzyl alcohol used in cosmetics?
Yes, Alpha-Methylbenzyl alcohol is also indexed as a cosmetic ingredient under the name Styralyl Alcohol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Alpha-Methylbenzyl alcohol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Alpha-Methylbenzyl alcohol have different safety status in cosmetics vs industrial chemicals?
Alpha-Methylbenzyl alcohol is classified GHS Danger (H302, H319, H315, H318, H335) in the chemicals database but is allowed in EU cosmetics.
Is Alpha-Methylbenzyl alcohol used outside industrial chemicals?
Alpha-Methylbenzyl alcohol also appears in cosmetics, pharmaceutical, cannabis databases.