What is the NOAEL for Allantoin?
Allantoin has 5 NOAEL studies in the database. The lowest reported value is 344S277G0Z UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Allantoin
Also known as: 5-25-15-00338, BRN 0102364, Caswell No. 024, EINECS 202-592-8, EPA Pesticide Chemical Code 085701 (+15 more)
CAS 97-59-6
Allantoin (CAS 97-59-6) is a chemical substance. Key regulatory status: REACH registered, 13 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
13
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Allantoin
CAS Number
97-59-6
DTXSID
DTXSID3020043
Molecular Formula
C4H6N4O3
InChI Key
POJWUDADGALRAB-UHFFFAOYSA-N
Monoisotopic Mass
158.04399
Synonyms
5-25-15-00338BRN 0102364Caswell No. 024EINECS 202-592-8EPA Pesticide Chemical Code 085701Hydantoin, 5-ureido-Uniderm A5-Ureido-2,4-imidazolidindionCutemol emollientUNII-344S277G0ZHerpecin L(2,5-diketoimidazolidin-4-yl)urea
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
41 records
Softener and conditionerHumectantFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
13 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Australia | Australian Pesticides and Veterinary Medicines Authority | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - specialized bath products - bath salts | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - general moisturizing - hand/body lotion | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 344S277G0Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 344S277G0Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 344S277G0Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 344S277G0Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Allantoin | 202-592-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ALLANTOIN
ChEMBL Phase
2
Adverse Events
66
Bioactivity
4
Frequently Asked Questions
What regulatory lists include Allantoin?
Allantoin appears on 11 regulatory/inventory lists including active_ingredient; Australia, inert_ingredient; non_food_use; Pesticides, pharmaceutical, and 8 more. Source: EPA CPDat.
Is Allantoin used in cosmetics?
Yes, Allantoin is also indexed as a cosmetic ingredient under the name Allantoin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Allantoin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Allantoin used outside industrial chemicals?
Allantoin also appears in cosmetics, pharmaceutical databases.