What is the NOAEL for (Z)-3-Hexen-1-ol?
(Z)-3-Hexen-1-ol has 16 NOAEL studies in the database. The lowest reported value is 11.75 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
(Z)-3-Hexen-1-ol
Also known as: cis-3-hexen-1-ol, 4-01-00-02141, BRN 1719712, EINECS 213-192-8, FEMA No. 2563 (+6 more)
CAS 928-96-1
(Z)-3-Hexen-1-ol (CAS 928-96-1) is a chemical substance. Key regulatory status: REACH registered, 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
16
SOURCE
chemical inventory jurisdictions
Regulatory lists
10
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
(Z)-3-Hexen-1-ol
CAS Number
928-96-1
DTXSID
DTXSID6022137
Molecular Formula
C6H12O
InChI Key
UFLHIIWVXFIJGU-ARJAWSKDSA-N
Monoisotopic Mass
100.088815
Synonyms
cis-3-hexen-1-ol4-01-00-02141BRN 1719712EINECS 213-192-8FEMA No. 2563beta-gamma-HexenolZ-3-HexenolNSC 74451UNII-V14F8G75P4(3Z)-hex-3-en-1-olBlatteralkohol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
FragranceDeodorizerSoftener and conditionerSolventHumectantViscosity modifierFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
10 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; Pesticides | EPA | CPCat |
| air; Cleaning products and household care - air freshener; detected; emissions | Elsevier | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| consumer_product | P&G | Proctor & Gamble |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 16 of 16 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =11.75 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| V14F8G75P4 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V14F8G75P4 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V14F8G75P4 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V14F8G75P4 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =4700 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =127 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =127 | mg/kg bw/day | NOAEL | oral: drinking water | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =127 | mg/kg bw/day | NOAEL | oral: drinking water | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 500 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =278.75 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 16 of 16 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | cis-hex-3-en-1-ol | 213-192-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
aroma_chemical
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CIS-3-HEXENOL
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include (Z)-3-Hexen-1-ol?
(Z)-3-Hexen-1-ol appears on 9 regulatory/inventory lists including inert_ingredient; Pesticides, air; Cleaning products and household care - air freshener; detected; emissions, inert_ingredient; non_food_use; Pesticides, and 6 more. Source: EPA CPDat.
Is (Z)-3-Hexen-1-ol used in cosmetics?
Yes, (Z)-3-Hexen-1-ol is also indexed as a cosmetic ingredient under the name Cis-3-Hexenol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for (Z)-3-Hexen-1-ol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is (Z)-3-Hexen-1-ol used outside industrial chemicals?
(Z)-3-Hexen-1-ol also appears in cosmetics, pharmaceutical, food safety, cannabis databases.