What is the NOAEL for Polyoxyethylene monohexadecyl ether?
Polyoxyethylene monohexadecyl ether has 100 NOAEL studies in the database. The lowest reported value is 11.1 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Polyoxyethylene monohexadecyl ether
Also known as: Hexadecylpoly(ethyleneoxy)ethanol, Oxyethylenated hexadecyl alcohol, Polyethylene glycol cetyl ether, Poly(oxy-1,2-ethanediyl), alpha-hexadecyl-omega-hydroxy-, Cetomacrogol (+14 more)
CAS 9004-95-9
Polyoxyethylene monohexadecyl ether (CAS 9004-95-9) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Polyoxyethylene monohexadecyl ether is classified GHS Danger (H315, H302, H318) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
100
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chemical inventory jurisdictions
Regulatory lists
6
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eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
22 fields
Name
Polyoxyethylene monohexadecyl ether
CAS Number
9004-95-9
DTXSID
DTXSID60858847
Synonyms
Hexadecylpoly(ethyleneoxy)ethanolOxyethylenated hexadecyl alcoholPolyethylene glycol cetyl etherPoly(oxy-1,2-ethanediyl), alpha-hexadecyl-omega-hydroxy-CetomacrogolPoly(oxy-1,2-ethanediyl), .alpha.-hexadecyl-.omega.-hydroxy-Cetyl poly(oxyethylene) etherEthosperse CL20Hexadecylpoly(ethyleneoxy) ethanolPolyethylene glycols monohexadecyl etherPoly(oxyethylene)cetyl etherPoly(oxyethylene)hexadecyl ether
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
52 records
Surfactant (surface active agent)EmulsifierCleaning agentWetting agent (non-aqueous)
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care - liniment | Danish Environmental Protection Agency | Danish EPA |
| pharmaceutical | US International Trade Commission | CPCat |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 50 of 100 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =11.1 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 0EV3Z43Y2I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0EV3Z43Y2I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0EV3Z43Y2I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0EV3Z43Y2I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2BB3L0ZO76 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2BB3L0ZO76 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2BB3L0ZO76 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2BB3L0ZO76 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 33D0C5D77R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 33D0C5D77R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 33D0C5D77R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 33D0C5D77R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 495CTZ441V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 495CTZ441V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 495CTZ441V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 495CTZ441V | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4ST6952Q67 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4ST6952Q67 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4ST6952Q67 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4ST6952Q67 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4TIK16VW41 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4TIK16VW41 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4TIK16VW41 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4TIK16VW41 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5KLY4IOG20 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5KLY4IOG20 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5KLY4IOG20 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5KLY4IOG20 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5QU14HKY1U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5QU14HKY1U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5QU14HKY1U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5QU14HKY1U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 683I13476K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 683I13476K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 683I13476K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 683I13476K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6X446K7Q0Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6X446K7Q0Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6X446K7Q0Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6X446K7Q0Y | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7Z6Q50934N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7Z6Q50934N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7Z6Q50934N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7Z6Q50934N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 94826GMB5B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 94826GMB5B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 94826GMB5B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 94826GMB5B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9E0067TYQH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 50 of 100 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
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ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Hexadecan- l-ol, ethoxylated | 500-014-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
emulsifier
Frequently Asked Questions
What regulatory lists include Polyoxyethylene monohexadecyl ether?
Polyoxyethylene monohexadecyl ether appears on 6 regulatory/inventory lists including Europe; Personal care - liniment, pharmaceutical, SCIL (9/2019), and 3 more. Source: EPA CPDat.
Is Polyoxyethylene monohexadecyl ether used in cosmetics?
Yes, Polyoxyethylene monohexadecyl ether is also indexed as a cosmetic ingredient under the name Ceteth-20. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Polyoxyethylene monohexadecyl ether come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Polyoxyethylene monohexadecyl ether have different safety status in cosmetics vs industrial chemicals?
Polyoxyethylene monohexadecyl ether is classified GHS Danger (H315, H302, H318) in the chemicals database but is allowed in EU cosmetics.
Is Polyoxyethylene monohexadecyl ether used outside industrial chemicals?
Polyoxyethylene monohexadecyl ether also appears in cosmetics databases.