What is the NOAEL for Gum arabic?
Gum arabic has 24 NOAEL studies in the database. The lowest reported value is 5C5403N26O UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Gum arabic
Also known as: Acacia senegal, EINECS 232-519-5, FEMA No. 2001, Gum arabic (Acacia senegal (L.) Willd.), Gum arabicum (+6 more)
CAS 9000-01-5
Gum arabic (CAS 9000-01-5) is a chemical substance. Key regulatory status: 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
24
SOURCE
chemical inventory jurisdictions
Regulatory lists
7
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Gum arabic
CAS Number
9000-01-5
DTXSID
DTXSID8020676
Synonyms
Acacia senegalEINECS 232-519-5FEMA No. 2001Gum arabic (Acacia senegal (L.) Willd.)Gum arabicumGum DragonNCI-C50748Starsol No. 1UNII-5C5403N26OAcacia senegal resinAcacia verek resin
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Film formerDeodorizerAdhesion/cohesion promoterFragranceStabilizing agentViscosity modifier
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
7 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 24 of 24 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 5C5403N26O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5C5403N26O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5C5403N26O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5C5403N26O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =760 | mg/kg bw/day | LEL | oral | Human | ToxValDB_EFSA |
| =2500 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_EFSA |
| =5220 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_EFSA |
| =7500 | mg/kg bw/day | LEL | oral | Mouse | ToxValDB_EFSA |
| =20000 | mg/kg bw/day | LEL | oral | Mouse | ToxValDB_EFSA |
| 800 | mg/kg bw/day | NOAEL | oral | rabbit | COSMOS_DB |
| 1600 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| =2500 | mg/kg bw/day | NOAEL | - | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 3117 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 5000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 6000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 7500 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 10000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 10647 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 13900 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 15000 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 25000 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 30000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 80000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 50000 | ppm | Top dose | Dosed feed | Mouse | NTP_ICE_cancer |
Showing 24 of 24 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
1
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Gum arabic?
Gum arabic appears on 6 regulatory/inventory lists including Europe; Personal care, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 3 more. Source: EPA CPDat.
Is Gum arabic used in cosmetics?
Yes, Gum arabic is also indexed as a cosmetic ingredient under the name Acacia Senegal Gum. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Gum arabic come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Gum arabic used outside industrial chemicals?
Gum arabic also appears in cosmetics, pharmaceutical, food safety, cannabis databases.