What is the NOAEL for Allyl Ionone?
Allyl Ionone has 8 NOAEL studies in the database. The lowest reported value is 8IP66F9ODG UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Allyl Ionone
Also known as: 1,6-Heptadien-3-one, 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-, 4-07-00-00833, Allyl cyclocitrylideneacetone, Allyl-alpha-ionone, BRN 3133731 (+10 more)
CAS 79-78-7
Allyl Ionone (CAS 79-78-7) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
Allyl Ionone is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H317).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
21 fields
Name
Allyl Ionone
CAS Number
79-78-7
DTXSID
DTXSID4047591
Molecular Formula
C16H24O
InChI Key
FXCYGAGBPZQRJE-ZHACJKMWSA-N
Monoisotopic Mass
232.182715
Synonyms
1,6-Heptadien-3-one, 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-4-07-00-00833Allyl cyclocitrylideneacetoneAllyl-alpha-iononeBRN 3133731Butenyl alpha-cyclocitrylidenemethyl ketoneCetone VCyclocitrylidenemethyl butenyl ketone, alpha-EINECS 201-225-9FEMA No. 2033Ionone, allyl alpha-1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-1,6-heptadien-3-one
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 8IP66F9ODG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8IP66F9ODG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8IP66F9ODG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8IP66F9ODG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 6480 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
| 4 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3184724
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Allyl Ionone?
Allyl Ionone appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Allyl Ionone used in cosmetics?
Yes, Allyl Ionone is also indexed as a cosmetic ingredient under the name Allyl Alpha-Ionone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Allyl Ionone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Allyl Ionone have different safety status in cosmetics vs industrial chemicals?
Allyl Ionone is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H317).
Is Allyl Ionone used outside industrial chemicals?
Allyl Ionone also appears in cosmetics, pharmaceutical, food safety, cannabis databases.