NOAEL Data REACH Registered Cosmetic Ingredient

Calcium hydrogen phosphate

Also known as: Phosphoric acid, calcium salt (1:1), Dicalcium phosphate, Calcium phosphate dibasic, Calcium phosphate (CaHPO4), A-Tab (+15 more)

CAS 7757-93-9

Calcium hydrogen phosphate (CAS 7757-93-9) is a chemical substance. Key regulatory status: REACH registered, 60 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Dicalcium Phosphate →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
60
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 26 fields
Name
Calcium hydrogen phosphate
CAS Number
7757-93-9
DTXSID
DTXSID20872529
Molecular Formula
Ca.H3O4P
InChI Key
FUFJGUQYACFECW-UHFFFAOYSA-L
Monoisotopic Mass
137.939486
Synonyms
Phosphoric acid, calcium salt (1:1)Dicalcium phosphateCalcium phosphate dibasicCalcium phosphate (CaHPO4)A-TabAnhydrous EmcompressBekapressBiofosCalcium acid phosphateCalcium dibasic phosphateCalcium hydrogen orthophosphateCalcium hydrogen phosphate (CaHPO4)

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 60 records
AbrasiveOpaciferFillerFlavouring and nutrientBiocideHumectantDrierEmulsifierThickening agentpH regulating agentLeavening agentAnti-caking agent

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 60 records
ListKeywordSource
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
inert_ingredient; non_food_use; PesticidesEPACPCat
active_ingredient; agricultural; PesticidesArizona Department of Environmental QualityState of Arizona
active_ingredient; agricultural; applied; PesticidesArizona Department of Environmental QualityState of Arizona
active_ingredient; PesticidesEPACPCat
active_ingredient; PesticidesEPACPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; PesticidesMN Department of Agriculture Pesticide Sales DatabaseCPCat
active_ingredient; agricultural; PesticidesUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; drinking_water; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)
agricultural; detected; fruits_and_vegetables; Pesticides; residueUSDAUnited States Department of Agriculture (USDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
L11K75P92JUNIIFDA UNII substance identifier--openFDA substances
L11K75P92JUNIIFDA UNII substance identifier--openFDA substances
L11K75P92JUNIIFDA UNII substance identifier--openFDA substances
L11K75P92JUNIIFDA UNII substance identifier--openFDA substances
=214mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
=240mg/kg bw/dayNOAEL (HED)oralRatToxValDB_PPRTV_(CPHEA)
=8mg/kg bw/dayRfD (provisional)oralHumanToxValDB_PPRTV_(CPHEA)

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredCalcium hydrogenorthophosphate231-826-1ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CALCIUM PHOSPHATE, DIBASIC
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

E341ii — ADI: 40 mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Calcium hydrogen phosphate?

Calcium hydrogen phosphate has 7 NOAEL studies in the database. The lowest reported value is L11K75P92J UNII. Source: openFDA substances.

What regulatory lists include Calcium hydrogen phosphate?

Calcium hydrogen phosphate appears on 8 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), inert_ingredient; non_food_use; Pesticides, active_ingredient; agricultural; Pesticides, and 5 more. Source: EPA CPDat.

Is Calcium hydrogen phosphate used in cosmetics?

Yes, Calcium hydrogen phosphate is also indexed as a cosmetic ingredient under the name Dicalcium Phosphate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Calcium hydrogen phosphate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Calcium hydrogen phosphate used outside industrial chemicals?

Calcium hydrogen phosphate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.