NOAEL Data REACH Registered Cosmetic Ingredient

(+)-Cedrol

Also known as: 1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8-tetramethyl-,(3R,3aS,6R,7R,8aS)-, 8beta H-Cedran-8-ol, 1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8-tetramethyl-, [3R-(3α,3aβ,6α,7β,8aα)]-, α-Cedrol, Cedrol (+15 more)

CAS 77-53-2

(+)-Cedrol (CAS 77-53-2) is a chemical substance. Key regulatory status: REACH registered, 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for Cedrol →

SOURCE noael studies public
NOAEL studies
12
SOURCE chemical inventory jurisdictions
Regulatory lists
10
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 26 fields
Name
(+)-Cedrol
CAS Number
77-53-2
DTXSID
DTXSID1041269
Molecular Formula
C15H26O
InChI Key
SVURIXNDRWRAFU-OGMFBOKVSA-N
Monoisotopic Mass
222.198365
Synonyms
1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8-tetramethyl-,(3R,3aS,6R,7R,8aS)-8beta H-Cedran-8-ol1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8-tetramethyl-, [3R-(3α,3aβ,6α,7β,8aα)]-α-CedrolCedrol8βH-Cedran-8-ol3R,3aS,6R,7R,8aS)-Octahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen-6-ol(3R,3AS,6R,7R,8aS)-3,6,8,8-tetramethyloctahydro-1H-3a,7-methanoazulen-6-olCedrol Nanomedicin(8α)-cedran-8-ol8-CEDROL[3R-(3α,3aβ,6α,7β,8aα)]-Octahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen-6-ol

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 58 records
Softener and conditionerDeodorizerNo specific technical functionFragranceHumectantFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 10 records
ListKeywordSource
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
Australia; Food and drug - smoking-related productsNew Zealand ESRCPCat
artificial_sweat; detected; emissions; Europe; Toys and children's productsDanish Environmental Protection AgencyDanish EPA
artificial_sweat; detected; emissions; Europe; Toys and children's productsDanish Environmental Protection AgencyDanish EPA
Cleaning products and household care - air freshener; EuropeDanish Environmental Protection AgencyDanish EPA
air; Cleaning products and household care - air freshener; detected; emissions; EuropeDanish Environmental Protection AgencyDanish EPA
IFRA TransparencyIFRAIFRA
EuropeEuropean CommissionFl@vis
consumer_productP&GProctor & Gamble
inert_ingredient; non_food_use; PesticidesEPACPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 12 of 12 studies
ValueUnitEndpointRouteSpeciesSource
5%Concentration, 5% incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
4%Concentration, one positive responseDermalHumanNTP_ICE_skin_sensitization
63ZM9703BOUNIIFDA UNII substance identifier--openFDA substances
63ZM9703BOUNIIFDA UNII substance identifier--openFDA substances
63ZM9703BOUNIIFDA UNII substance identifier--openFDA substances
63ZM9703BOUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
8%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
5184ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
3240ug/cm2Induction dose per skin area, 5% incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
2592ug/cm2Induction dose per skin area, one positive responseDermalHumanNTP_ICE_skin_sensitization
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 12 of 12 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered[3R-(3α,3aβ,6α,7β,8aα)]-octahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen-6-ol201-035-6ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
terpene
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CEDROL
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
View full pharmaceutical profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for (+)-Cedrol?

(+)-Cedrol has 12 NOAEL studies in the database. The lowest reported value is 4 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.

What regulatory lists include (+)-Cedrol?

(+)-Cedrol appears on 9 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Australia; Food and drug - smoking-related products, artificial_sweat; detected; emissions; Europe; Toys and children's products, and 6 more. Source: EPA CPDat.

Is (+)-Cedrol used in cosmetics?

Yes, (+)-Cedrol is also indexed as a cosmetic ingredient under the name Cedrol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for (+)-Cedrol come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is (+)-Cedrol used outside industrial chemicals?

(+)-Cedrol also appears in cosmetics, pharmaceutical, cannabis databases.