What is the NOAEL for 3-Methylbut-3-en-1-ol?
3-Methylbut-3-en-1-ol has 6 NOAEL studies in the database. The lowest reported value is 0.274 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
3-Methylbut-3-en-1-ol
Also known as: EINECS 212-110-8, UNII-KJ25C8CPFA, 2-methyl-4-hydroxybut-1-ene, Delta(3)-isopentenyl alcohol, Methallyl carbinol (+1 more)
CAS 763-32-6
3-Methylbut-3-en-1-ol (CAS 763-32-6) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
3-Methylbut-3-en-1-ol is classified GHS Danger (H226, H318, H373) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
3-Methylbut-3-en-1-ol
CAS Number
763-32-6
DTXSID
DTXSID4052506
Molecular Formula
C5H10O
InChI Key
CPJRRXSHAYUTGL-UHFFFAOYSA-N
Monoisotopic Mass
86.073165
Synonyms
EINECS 212-110-8UNII-KJ25C8CPFA2-methyl-4-hydroxybut-1-eneDelta(3)-isopentenyl alcoholMethallyl carbinolMethyl-3-but-3-en-1-ol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.274 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| KJ25C8CPFA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KJ25C8CPFA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KJ25C8CPFA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KJ25C8CPFA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >5440 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3-methylbut-3-en-1-ol | 212-110-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3561140
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 3-Methylbut-3-en-1-ol?
3-Methylbut-3-en-1-ol appears on 3 regulatory/inventory lists including active_ingredient; Europe; Pesticides, IFRA Transparency, Europe. Source: EPA CPDat.
Is 3-Methylbut-3-en-1-ol used in cosmetics?
Yes, 3-Methylbut-3-en-1-ol is also indexed as a cosmetic ingredient under the name 3-Isopentenol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-Methylbut-3-en-1-ol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does 3-Methylbut-3-en-1-ol have different safety status in cosmetics vs industrial chemicals?
3-Methylbut-3-en-1-ol is classified GHS Danger (H226, H318, H373) in the chemicals database but is allowed in EU cosmetics.
Is 3-Methylbut-3-en-1-ol used outside industrial chemicals?
3-Methylbut-3-en-1-ol also appears in cosmetics, pharmaceutical, cannabis databases.