What is the NOAEL for Methoxatin?
Methoxatin has 4 NOAEL studies in the database. The lowest reported value is 47819QGH5L UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Methoxatin
Also known as: 4,5-Dihydro-4,5-dioxo-1-H-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylic acid, Pqq coenzyme, Pqq cofactor, Pyrrolo-quinoline quinone, 2,7,9-Tricarboxypyrroloquinoline quinone (+7 more)
CAS 72909-34-3
Methoxatin (CAS 72909-34-3) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
View cosmetic safety profile for Pyrroloquinoline Quinone (PQQ) →
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
Methoxatin
CAS Number
72909-34-3
DTXSID
DTXSID3041162
Molecular Formula
C14H6N2O8
InChI Key
MMXZSJMASHPLLR-UHFFFAOYSA-N
Monoisotopic Mass
330.012415
Synonyms
4,5-Dihydro-4,5-dioxo-1-H-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylic acidPqq coenzymePqq cofactorPyrrolo-quinoline quinone2,7,9-Tricarboxypyrroloquinoline quinone2,4,6-tricarboxylic-pyrrolo[2,3-5,6]quinoline 8,9-quinone2,7,9-tricarboxy-1H-pyrrolo(2,3-f)quinoline-4,5-dione4,5-Dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-5,6]quinoline-2,7,9-tricarboxylic acidPQQcoenzyme PQQpyrroloquinoline quinone
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
HumectantAntioxidantSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 47819QGH5L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 47819QGH5L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 47819QGH5L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 47819QGH5L | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
PYRROLOQUINOLINE QUINONE
ChEMBL Phase
Not listed
Adverse Events
3
Bioactivity
3
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
FDA GRAS: At the notifier's request, FDA ceased to evaluate this notice
View full food safety profile →Frequently Asked Questions
What regulatory lists include Methoxatin?
Methoxatin appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is Methoxatin used in cosmetics?
Yes, Methoxatin is also indexed as a cosmetic ingredient under the name Pyrroloquinoline Quinone (PQQ). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Methoxatin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Methoxatin used outside industrial chemicals?
Methoxatin also appears in cosmetics, pharmaceutical, food safety databases.