NOAEL Data REACH Registered Cosmetic Ingredient

Escin

Also known as: Aescin, UNII-RUU8G67GQM

CAS 6805-41-0

Escin (CAS 6805-41-0) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Escin →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields
Name
Escin
CAS Number
6805-41-0
DTXSID
DTXSID901021535
Molecular Formula
2C55H86O24
InChI Key
YFESOSRPNPYODN-RSMWSHJLSA-N
Monoisotopic Mass
2261.101807
Synonyms
AescinUNII-RUU8G67GQM

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records
HumectantNo specific technical function

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
RUU8G67GQMUNIIFDA UNII substance identifier--openFDA substances
RUU8G67GQMUNIIFDA UNII substance identifier--openFDA substances
RUU8G67GQMUNIIFDA UNII substance identifier--openFDA substances
RUU8G67GQMUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredEscin229-880-6ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Plant Extract
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL escin
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Escin?

Escin has 4 NOAEL studies in the database. The lowest reported value is RUU8G67GQM UNII. Source: openFDA substances.

Is Escin used in cosmetics?

Yes, Escin is also indexed as a cosmetic ingredient under the name Escin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Escin come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Escin used outside industrial chemicals?

Escin also appears in cosmetics, pharmaceutical databases.