What is the NOAEL for Sodium 2-methoxy-5-nitrophenolate?
Sodium 2-methoxy-5-nitrophenolate has 15 NOAEL studies in the database. The lowest reported value is 0.003 mg/kg bw/day in Consumers. Source: EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx.
NOAEL Data
Cosmetic Ingredient
Sodium 2-methoxy-5-nitrophenolate
Also known as: Phenol, 2-methoxy-5-nitro-, sodium salt, sodium 5-nitroguaiacolate, 5-Nitroguaiacol sodium salt, Sodium 2-methoxy-5-nitrophenoxide, EPA Pesticide Chemical Code 129075 (+3 more)
CAS 67233-85-6
Sodium 2-methoxy-5-nitrophenolate (CAS 67233-85-6) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
View cosmetic safety profile for Sodium 5-Nitroguaiacolate →
Cross-Vertical Regulatory Divergence
Sodium 2-methoxy-5-nitrophenolate is classified GHS Danger (H302, H319, H242, H318, H411) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
15
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Sodium 2-methoxy-5-nitrophenolate
CAS Number
67233-85-6
DTXSID
DTXSID0035790
Molecular Formula
C7H7NO4.Na
InChI Key
KBRKFTKQRMYINW-UHFFFAOYSA-M
Synonyms
Phenol, 2-methoxy-5-nitro-, sodium saltsodium 5-nitroguaiacolate5-Nitroguaiacol sodium saltSodium 2-methoxy-5-nitrophenoxideEPA Pesticide Chemical Code 129075Atonik G2-Methoxy-5-nitrophenol sodium saltUNII-A1RBP9328O
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 15 of 15 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.003 | mg/kg bw/day | ADI | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =0.003 | mg/kg bw/day | ADI | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =0.045 | mg/kg bw/day | ARfD | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =0.045 | mg/kg bw/day | ARfD | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| A1RBP9328O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| A1RBP9328O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| A1RBP9328O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| A1RBP9328O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.3 | mg/kg bw/day | NOAEL | oral | Dog | ToxValDB_EFSA |
| =0.3 | mg/kg bw/day | NOAEL | oral: unspecified | Dog | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =0.7 | mg/kg bw/day | NOAEL | oral | Dog | ToxValDB_EFSA |
| =0.7 | mg/kg bw/day | NOAEL | oral: unspecified | Dog | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =13.6 | mg/kg bw/day | NOAEL | oral | Rabbit | ToxValDB_EFSA |
| =13.6 | mg/kg bw/day | NOAEL | - | Rabbit | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =300 | mg/kg bw/day | NOAEL | - | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Showing 15 of 15 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Sodium 2-methoxy-5-nitrophenolate?
Sodium 2-methoxy-5-nitrophenolate appears on 1 regulatory/inventory list including active_ingredient; Europe; Pesticides. Source: EPA CPDat.
Is Sodium 2-methoxy-5-nitrophenolate used in cosmetics?
Yes, Sodium 2-methoxy-5-nitrophenolate is also indexed as a cosmetic ingredient under the name Sodium 5-Nitroguaiacolate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium 2-methoxy-5-nitrophenolate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Sodium 2-methoxy-5-nitrophenolate have different safety status in cosmetics vs industrial chemicals?
Sodium 2-methoxy-5-nitrophenolate is classified GHS Danger (H302, H319, H242, H318, H411) in the chemicals database but is allowed in EU cosmetics.
Is Sodium 2-methoxy-5-nitrophenolate used outside industrial chemicals?
Sodium 2-methoxy-5-nitrophenolate also appears in cosmetics, cannabis databases.