What is the NOAEL for Sodium ascorbyl phosphate?
Sodium ascorbyl phosphate has 7 NOAEL studies in the database. The lowest reported value is 5.2 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sodium ascorbyl phosphate
Also known as: L-Ascorbic acid, 2-monophosphate, trisodium salt, Sodium ascorbyl monophosphate, Sodium L-Ascorbyl-2-Phosphate, Trisodium ascorbate-2-phosphate, Trisodium mono-(5-(1,2-dihydroxethyl)-4-oxido-2-oxo-2,5-dihydro-furan-3-yl)phosphate (+3 more)
CAS 66170-10-3
Sodium ascorbyl phosphate (CAS 66170-10-3) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Sodium Ascorbyl Phosphate →
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Sodium ascorbyl phosphate
CAS Number
66170-10-3
DTXSID
DTXSID601014965
Molecular Formula
C6H9O9P.3Na
InChI Key
YRWWOAFMPXPHEJ-OFBPEYICSA-K
Monoisotopic Mass
324.967727
Synonyms
L-Ascorbic acid, 2-monophosphate, trisodium saltSodium ascorbyl monophosphateSodium L-Ascorbyl-2-PhosphateTrisodium ascorbate-2-phosphateTrisodium mono-(5-(1,2-dihydroxethyl)-4-oxido-2-oxo-2,5-dihydro-furan-3-yl)phosphateAscorbic acid phosphate sodium saltL-Ascorbic acid, 2-(dihydrogen phosphate), sodium salt (1:3)EC 425-180-1
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
Antioxidant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =5.2 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 836SJG51DR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 836SJG51DR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 836SJG51DR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 836SJG51DR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =90.3 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =424.1 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | trisodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-5-oxo-4-(phosphonooxy)-2,5-dihydrofuran-3-olate | 425-180-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Sodium ascorbyl phosphate?
Sodium ascorbyl phosphate appears on 2 regulatory/inventory lists including Europe; Personal care, Canada; Personal care; Substances in PCP - Canada (4/2014). Source: EPA CPDat.
Is Sodium ascorbyl phosphate used in cosmetics?
Yes, Sodium ascorbyl phosphate is also indexed as a cosmetic ingredient under the name Sodium Ascorbyl Phosphate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium ascorbyl phosphate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Sodium ascorbyl phosphate used outside industrial chemicals?
Sodium ascorbyl phosphate also appears in cosmetics, cannabis databases.