NOAEL Data REACH Registered Cosmetic Ingredient

Glucosamine hydrochloride

Also known as: 2-Amino-D-glucose, EINECS 200-638-1, Glucopyranose, 2-amino-2-deoxy-, hydrochloride, D-, D-Glucosamine monohydrochloride, Glucosamine HCl (+1 more)

CAS 66-84-2

Glucosamine hydrochloride (CAS 66-84-2) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for Glucosamine HCl →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
Glucosamine hydrochloride
CAS Number
66-84-2
DTXSID
DTXSID5037236
Molecular Formula
C6H13NO5.ClH
InChI Key
QKPLRMLTKYXDST-NSEZLWDYSA-N
Monoisotopic Mass
215.05605
Synonyms
2-Amino-D-glucoseEINECS 200-638-1Glucopyranose, 2-amino-2-deoxy-, hydrochloride, D-D-Glucosamine monohydrochlorideGlucosamine HClUNII-750W5330FY

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 14 records
Anti-static agentSoftener and conditionerpH regulating agentFlavouring and nutrient

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
750W5330FYUNIIFDA UNII substance identifier--openFDA substances
750W5330FYUNIIFDA UNII substance identifier--openFDA substances
750W5330FYUNIIFDA UNII substance identifier--openFDA substances
750W5330FYUNIIFDA UNII substance identifier--openFDA substances
=2130mg/kg bw/dayNOAELoralRatToxValDB_EFSA
=2130mg/kg bw/dayNOAEL-RatEFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx
=2130mg/kg bw/dayNOAEL-RatEFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredGlucosamine hydrochloride200-638-1ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
81
Bioactivity
0
View full pharmaceutical profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Glucosamine hydrochloride?

Glucosamine hydrochloride has 7 NOAEL studies in the database. The lowest reported value is 750W5330FY UNII. Source: openFDA substances.

Is Glucosamine hydrochloride used in cosmetics?

Yes, Glucosamine hydrochloride is also indexed as a cosmetic ingredient under the name Glucosamine HCl. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Glucosamine hydrochloride come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Glucosamine hydrochloride used outside industrial chemicals?

Glucosamine hydrochloride also appears in cosmetics, pharmaceutical, cannabis databases.