What is the NOAEL for Hexadecyltrimethylammonium methyl sulphate?
Hexadecyltrimethylammonium methyl sulphate has 4 NOAEL studies in the database. The lowest reported value is 277IG2X9QC UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Hexadecyltrimethylammonium methyl sulphate
Also known as: 1-Hexadecanaminium, N,N,N-trimethyl-, methyl sulfate, 1-Hexadecanaminium, N,N,N-trimethyl-, methyl sulfate (1:1), Cetrimonium methosulfate, Ammonium, hexadecyltrimethyl, methyl sulfate, EINECS 265-352-1 (+2 more)
CAS 65060-02-8
Hexadecyltrimethylammonium methyl sulphate (CAS 65060-02-8) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Hexadecyltrimethylammonium methyl sulphate is classified GHS Danger (H302, H314, H315, H318, H400, H410) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
13 fields
Name
Hexadecyltrimethylammonium methyl sulphate
CAS Number
65060-02-8
DTXSID
DTXSID3070173
Molecular Formula
C19H42N.CH4O4S
InChI Key
OEWKLERKHURFTB-UHFFFAOYSA-M
Monoisotopic Mass
396.314755
Synonyms
1-Hexadecanaminium, N,N,N-trimethyl-, methyl sulfate1-Hexadecanaminium, N,N,N-trimethyl-, methyl sulfate (1:1)Cetrimonium methosulfateAmmonium, hexadecyltrimethyl, methyl sulfateEINECS 265-352-1UNII-277IG2X9QCN,N,N-Trimethyl-1-hexadecanaminium methyl sulfate
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
13 records
Surfactant (surface active agent)BiocideAnti-static agentEmulsifierSoftener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 277IG2X9QC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 277IG2X9QC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 277IG2X9QC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 277IG2X9QC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Hexadecyltrimethylammonium methyl sulphate | 265-352-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
surfactant
Frequently Asked Questions
Is Hexadecyltrimethylammonium methyl sulphate used in cosmetics?
Yes, Hexadecyltrimethylammonium methyl sulphate is also indexed as a cosmetic ingredient under the name Cetrimonium Methosulfate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Hexadecyltrimethylammonium methyl sulphate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Hexadecyltrimethylammonium methyl sulphate have different safety status in cosmetics vs industrial chemicals?
Hexadecyltrimethylammonium methyl sulphate is classified GHS Danger (H302, H314, H315, H318, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Is Hexadecyltrimethylammonium methyl sulphate used outside industrial chemicals?
Hexadecyltrimethylammonium methyl sulphate also appears in cosmetics databases.