What is the NOAEL for Oxiconazole nitrate?
Oxiconazole nitrate has 5 NOAEL studies in the database. The lowest reported value is RQ8UL4C17S UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Oxiconazole nitrate
Also known as: 2',4'-Dichloro-2-imidazol-1-ylacetophenone (Z)-(o-(2,4-dichlorobenzyl))oxime nitrate, EINECS 264-730-3, Oxiconazole mono-nitrate (Z)-isomer, UNII-RQ8UL4C17S, 1-[(2Z)-2-{[(2,4-dichlorobenzyl)oxy]imino}-2-(2,4-dichlorophenyl)ethyl]-1H-imidazol-3-ium nitrate (+1 more)
CAS 64211-46-7
Oxiconazole nitrate (CAS 64211-46-7) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB.
Cross-Vertical Regulatory Divergence
Oxiconazole nitrate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H332).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Oxiconazole nitrate
CAS Number
64211-46-7
DTXSID
DTXSID2045943
Molecular Formula
C18H13Cl4N3O.HNO3
InChI Key
WVNOAGNOIPTWPT-NDUABGMUSA-N
Monoisotopic Mass
489.976916
Synonyms
2',4'-Dichloro-2-imidazol-1-ylacetophenone (Z)-(o-(2,4-dichlorobenzyl))oxime nitrateEINECS 264-730-3Oxiconazole mono-nitrate (Z)-isomerUNII-RQ8UL4C17S1-[(2Z)-2-{[(2,4-dichlorobenzyl)oxy]imino}-2-(2,4-dichlorophenyl)ethyl]-1H-imidazol-3-ium nitrate2',4'-dichloro-2-imidazol-1-ylacetophenone (Z)-[OO-(2,4-dichlorobenzyl)oxime] mononitrate
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| RQ8UL4C17S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RQ8UL4C17S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RQ8UL4C17S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RQ8UL4C17S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =2458 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 5 of 5 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
OXICONAZOLE NITRATE
ChEMBL Phase
4
Adverse Events
2
Bioactivity
5
Frequently Asked Questions
Is Oxiconazole nitrate used in cosmetics?
Yes, Oxiconazole nitrate is also indexed as a cosmetic ingredient under the name Oxiconazole. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Oxiconazole nitrate come from?
Safety data is sourced from EPA ToxValDB, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Oxiconazole nitrate have different safety status in cosmetics vs industrial chemicals?
Oxiconazole nitrate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H332).
Is Oxiconazole nitrate used outside industrial chemicals?
Oxiconazole nitrate also appears in cosmetics, pharmaceutical databases.