Also known as: Caswell No. 855, EINECS 200-543-5, EPA Pesticide Chemical Code 080201, RCRA waste number U219, Sulourea (+13 more)
CAS 62-56-6
Thiourea (CAS 62-56-6) is a chemical substance with GHS signal word Warning; key hazard signal: H351; H361d ***; H302; H411. Key regulatory status: California Proposition 65, REACH registered, 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, IARC, ECHA REACH, CA Prop 65, ILO ICSC, EPA TRI.
Thiourea is prohibited in EU cosmetics but has active industrial GHS classifications (H351, H361d, H302, H411).
CAS, identifiers, formula, and alternate names for the matched substance record.
Carcinogenic hazard classification from IARC monograph evaluations.
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 3 | Not classifiable | 2000 | Sup 7, 79 |
California OEHHA listing status and toxicity category.
| Chemical | Toxicity Type | Cancer | Developmental | Listed |
|---|---|---|---|---|
| - | cancer | Yes | No | - |
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Carc. 2; Repr. 2; Acute Tox. 4 *; Aquatic Chronic 2 | H351; H361d ***; H302; H411 | GHS08; GHS07; GHS09 | Warning |
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| Short-term Effects | The substance is irritating to the eyes. |
| Long-term Effects | Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the thyroid. This substance is possibly carcinogenic to humans. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Cons electronics mech appliances and machinery; Europe | Danish Environmental Protection Agency | Danish EPA |
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| OEHHA Proposition 65 (3/2019) | STATE OF CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY | OEHHA Proposition 65 List |
| fracking; water | NY Department of Conservation | CPCat |
| OEHHA Proposition 65 (1/2023) | California Office of Environmental Health Hazard Assessment | OEHHA Proposition 65 List |
| banned; Europe; Personal care | European Commission | CosIng |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| SQE10 | ug/day | California Proposition 65 NSRL | - | - | California Proposition 65 |
| SQE10 | ug/day | California Proposition 65 NSRL | - | - | California Proposition 65 |
| SQE10 | ug/day | California Proposition 65 NSRL | - | - | California Proposition 65 |
| SQE10 | ug/day | California Proposition 65 NSRL | - | - | California Proposition 65 |
| SQEcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| SQEcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| SQEcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| SQEcancer | listing type | California Proposition 65 listing | - | - | California Proposition 65 |
| =1 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| GYV9AM2QAG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GYV9AM2QAG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GYV9AM2QAG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GYV9AM2QAG | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3 | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 3 | unitless | IARC group | - | - | NTP_ICE_cancer |
| >=0.17 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| >0.195 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| =3 | mg/kg bw/day | LEL | injection | Rat | ToxValDB_ECHA_IUCLID |
| =25 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =131 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =557.5 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =2000 | ppm | LOAEC | oral | Rat | ToxValDB_ECHA_IUCLID |
| ~20 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| ~21 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =27.5 | mg/kg bw/day | LOAEL | oral | Rat | INCHEM_WHO_cicads_cicads_cicad49 |
| =30 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =50 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| ~55 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| ~59 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| <300 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =5 | mg/kg bw/day | LOEL | injection | Rat | ToxValDB_ECOTOX |
| ~70 | mg/kg bw/day | LOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =6.88 | mg/kg bw/day | NOAEL | oral | Rat | INCHEM_WHO_cicads_cicads_cicad49 |
| =25 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=27.5 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=1.73 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=2.65 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =12 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 39 of 39 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | thiourea; thiocarbamide | 200-543-5 | ECHA overview → |
TRI hazard and reporting flags for the matched chemical.
| Chemical | Category | Flags |
|---|---|---|
| Thiourea | - | - |
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Same-CAS food additive, ADI, and GRAS records where available.
1 food-safety record found.
View full food safety profile →Thiourea (CAS 62-56-6) is classified under EU CLP Annex VI as Carc. 2; Repr. 2; Acute Tox. 4 *; Aquatic Chronic 2 with signal word Warning. Hazard statements: H351; H361d ***; H302; H411. Source: EU CLP Annex VI (ECHA).
Thiourea has 39 NOAEL studies in the database. The lowest reported value is 10 ug/day. Source: California Proposition 65.
Thiourea appears on 7 regulatory/inventory lists including Cons electronics mech appliances and machinery; Europe, active_ingredient; Europe; Pesticides, OEHHA Proposition 65 (3/2019), and 4 more. Source: EPA CPDat.
Thiourea is classified by IARC as Group 3 — not classifiable as to its carcinogenicity to humans (evaluated 2000). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
Yes, Thiourea is listed under California Proposition 65 for cancer. Source: California OEHHA Proposition 65.
Yes, Thiourea is also indexed as a cosmetic ingredient under the name Thiourea ⚠️. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, EPA DSSTox, IARC Monographs, ECHA REACH, California Proposition 65, ILO/WHO ICSC, EPA Toxics Release Inventory, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Thiourea is prohibited in EU cosmetics but has active industrial GHS classifications (H351, H361d, H302, H411).
Thiourea also appears in cosmetics, pharmaceutical, food safety databases.