NOAEL Data Cosmetic Ingredient

Acetyl hexapeptide-3

Also known as: N-[(3S)-3-Acetamido-5-carboxy-1-penten-2-yl]-L-alpha-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-argininamide, L-Argininamide, N-[(2S)-2-(acetylamino)-4-carboxy-1-methylenebutyl]-L-α-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-, l-Argininamide, N-acetyl-l-alpha-glutamyl-l-alpha-glutamyl-l-methionyl-l-glutaminyll-l-arginyl-, Acetyl-glu-glu-met-gln-arg-arg-amide, UNII-L4EL31FWIL (+1 more)

CAS 616204-22-9

Acetyl hexapeptide-3 (CAS 616204-22-9) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Acetyl Hexapeptide-8 →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
Acetyl hexapeptide-3
CAS Number
616204-22-9
DTXSID
DTXSID201021291
Molecular Formula
C35H62N14O11S
InChI Key
AJLNZWYOJAWBCR-OOPVGHQCSA-N
Monoisotopic Mass
886.44432
Synonyms
N-[(3S)-3-Acetamido-5-carboxy-1-penten-2-yl]-L-alpha-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-argininamideL-Argininamide, N-[(2S)-2-(acetylamino)-4-carboxy-1-methylenebutyl]-L-α-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-l-Argininamide, N-acetyl-l-alpha-glutamyl-l-alpha-glutamyl-l-methionyl-l-glutaminyll-l-arginyl-Acetyl-glu-glu-met-gln-arg-arg-amideUNII-L4EL31FWILHexapeptide 3

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
HumectantSoftener and conditioner

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
Canada; pharmaceuticalDrugBankDrugBank

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
L4EL31FWILUNIIFDA UNII substance identifier--openFDA substances
L4EL31FWILUNIIFDA UNII substance identifier--openFDA substances
L4EL31FWILUNIIFDA UNII substance identifier--openFDA substances
L4EL31FWILUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Acetyl hexapeptide-3?

Acetyl hexapeptide-3 has 4 NOAEL studies in the database. The lowest reported value is L4EL31FWIL UNII. Source: openFDA substances.

What regulatory lists include Acetyl hexapeptide-3?

Acetyl hexapeptide-3 appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.

Is Acetyl hexapeptide-3 used in cosmetics?

Yes, Acetyl hexapeptide-3 is also indexed as a cosmetic ingredient under the name Acetyl Hexapeptide-8. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Acetyl hexapeptide-3 come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Acetyl hexapeptide-3 used outside industrial chemicals?

Acetyl hexapeptide-3 also appears in cosmetics databases.