What is the NOAEL for 2,5-Pyrrolidinedione, 1-hydroxy-?
2,5-Pyrrolidinedione, 1-hydroxy- has 4 NOAEL studies in the database. The lowest reported value is MJE3791M4T UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2,5-Pyrrolidinedione, 1-hydroxy-
Also known as: EINECS 228-001-3, UNII-MJE3791M4T
CAS 6066-82-6
2,5-Pyrrolidinedione, 1-hydroxy- (CAS 6066-82-6) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
2,5-Pyrrolidinedione, 1-hydroxy-
CAS Number
6066-82-6
DTXSID
DTXSID7064102
Molecular Formula
C4H5NO3
InChI Key
NQTADLQHYWFPDB-UHFFFAOYSA-N
Monoisotopic Mass
115.026943
Synonyms
EINECS 228-001-3UNII-MJE3791M4T
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Softener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| MJE3791M4T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| MJE3791M4T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| MJE3791M4T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| MJE3791M4T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | N-hydroxysuccinimide | 228-001-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL403753
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
Is 2,5-Pyrrolidinedione, 1-hydroxy- used in cosmetics?
Yes, 2,5-Pyrrolidinedione, 1-hydroxy- is also indexed as a cosmetic ingredient under the name N-HYDROXYSUCCINIMIDE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,5-Pyrrolidinedione, 1-hydroxy- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 2,5-Pyrrolidinedione, 1-hydroxy- used outside industrial chemicals?
2,5-Pyrrolidinedione, 1-hydroxy- also appears in cosmetics, pharmaceutical databases.