What is the NOAEL for Glycine hydrochloride?
Glycine hydrochloride has 5 NOAEL studies in the database. The lowest reported value is 225ZLC74HX UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Glycine hydrochloride
Also known as: Aminoacetic acid hydrochloride, Glycine, hydrochloride, Glycine, hydrochloride (1:1), EINECS 227-841-8, Glycocoll hydrochloride (+1 more)
CAS 6000-43-7
Glycine hydrochloride (CAS 6000-43-7) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Glycine hydrochloride is classified GHS Danger (H314, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Glycine hydrochloride
CAS Number
6000-43-7
DTXSID
DTXSID7064079
Molecular Formula
C2H5NO2.ClH
InChI Key
IVLXQGJVBGMLRR-UHFFFAOYSA-N
Monoisotopic Mass
111.008706
Synonyms
Aminoacetic acid hydrochlorideGlycine, hydrochlorideGlycine, hydrochloride (1:1)EINECS 227-841-8Glycocoll hydrochlorideUNII-225ZLC74HX
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
pH regulating agent
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 225ZLC74HX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 225ZLC74HX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 225ZLC74HX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 225ZLC74HX | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =3340 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Glycine hydrochloride | 227-841-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Frequently Asked Questions
Is Glycine hydrochloride used in cosmetics?
Yes, Glycine hydrochloride is also indexed as a cosmetic ingredient under the name Glycine HCl. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Glycine hydrochloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Glycine hydrochloride have different safety status in cosmetics vs industrial chemicals?
Glycine hydrochloride is classified GHS Danger (H314, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Is Glycine hydrochloride used outside industrial chemicals?
Glycine hydrochloride also appears in cosmetics databases.