What is the NOAEL for Lactitol?
Lactitol has 5 NOAEL studies in the database. The lowest reported value is L2B0WJF7ZY UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Lactitol
Also known as: EINECS 209-566-5, Lactitolum, UNII-L2B0WJF7ZY, D-lactitol
CAS 585-86-4
Lactitol (CAS 585-86-4) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
7 fields
Name
Lactitol
CAS Number
585-86-4
DTXSID
DTXSID9044247
Synonyms
EINECS 209-566-5LactitolumUNII-L2B0WJF7ZYD-lactitol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
HumectantSoftener and conditionerFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| L2B0WJF7ZY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L2B0WJF7ZY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L2B0WJF7ZY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L2B0WJF7ZY | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| <625 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_HESS |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 4-O-β-D-galactopyranosyl-D-glucitol | 209-566-5 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Humectant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
LACTITOL
ChEMBL Phase
4
Adverse Events
2
Bioactivity
2
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E966 — ADI: NOT SPECIFIED mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include Lactitol?
Lactitol appears on 2 regulatory/inventory lists including pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.
Is Lactitol used in cosmetics?
Yes, Lactitol is also indexed as a cosmetic ingredient under the name Lactitol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Lactitol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Lactitol used outside industrial chemicals?
Lactitol also appears in cosmetics, pharmaceutical, food safety databases.