What is the NOAEL for L-Ascorbic acid calcium salt (2:1)?
L-Ascorbic acid calcium salt (2:1) has 6 NOAEL studies in the database. The lowest reported value is J96U0ZD4Y6 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
L-Ascorbic acid calcium salt (2:1)
Also known as: Calcium ascorbate anhydrous, Hemicalcium ascorbate, Calcium ascorbate, Ascorbic acid calcium salt, Calci-C (+3 more)
CAS 5743-27-1
L-Ascorbic acid calcium salt (2:1) (CAS 5743-27-1) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
L-Ascorbic acid calcium salt (2:1)
CAS Number
5743-27-1
DTXSID
DTXSID40110036
Molecular Formula
2C6H8O6.Ca
InChI Key
BLORRZQTHNGFTI-ZZMNMWMASA-L
Monoisotopic Mass
392.026767
Synonyms
Calcium ascorbate anhydrousHemicalcium ascorbateCalcium ascorbateAscorbic acid calcium saltCalci-CCalcium L-ascorbateEINECS 227-261-5UNII-J96U0ZD4Y6
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
AntioxidantSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe; supplements | EU | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| J96U0ZD4Y6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J96U0ZD4Y6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J96U0ZD4Y6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J96U0ZD4Y6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 2500 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 6 of 6 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CALCIUM ASCORBATE
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E302 — ADI: NOT SPECIFIED mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include L-Ascorbic acid calcium salt (2:1)?
L-Ascorbic acid calcium salt (2:1) appears on 3 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe; supplements, inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is L-Ascorbic acid calcium salt (2:1) used in cosmetics?
Yes, L-Ascorbic acid calcium salt (2:1) is also indexed as a cosmetic ingredient under the name CALCIUM ASCORBATE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for L-Ascorbic acid calcium salt (2:1) come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is L-Ascorbic acid calcium salt (2:1) used outside industrial chemicals?
L-Ascorbic acid calcium salt (2:1) also appears in cosmetics, pharmaceutical, food safety, cannabis databases.